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Growth Differentiation Factor 5 (GDF5) Core Promoter Polymorphism Is Not Associated with Susceptibility to Osteoarthritis of the Knee in the Korean Population

Cao Z, Lee HS, Song JH, Yoon JW, Park YK, Nam SW, Lee JY, Park WS

  • KMID: 2277579
  • Korean J Pathol.
  • 2010 Aug;44(4):404-409.
BACKGROUND: Osteoarthritis (OA) is a common disease characterized by degenerating joint cartilage in the knee, hip, and hand. A functional single nucleotide polymorphism (SNP) +104T/C; rs143383 in the 5' untranslated...
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MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes

Zhang Y, Jia J, Yang S, Liu X, Ye S, Tian H

Osteoarthritis is a common cause of functional deterioration in older adults and is an immense burden on the aging population. Altered chondrogenesis is the most important pathophysiological process involved in...
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Expression of cartilage derived morphogenic protein in pleomorphic adenoma

Lee HJ, Kim CH, Kim KW

  • KMID: 2190279
  • J Korean Assoc Oral Maxillofac Surg.
  • 2007 Jun;33(3):247-255.
The bone morphogenic protein(BMP) can promote migration and growth of mesenchymal cells and initiate process for bone and cartilage formation. Cartilage-derived morphogenic protein(CDMP)-1 and -2 belong to the bone morphogenetic...
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Identification of a GDF5 Mutation in a Korean Patient with Brachydactyly Type C without Foot Involvement

Seo SH, Park MJ, Kim SH, Kim OH, Park S, Cho SI, Park SS, Seong MW

Brachydactyly type C (BDC) is characterized by shortening of the middle phalanges of the index, middle, and little fingers. Hyperphalangy of the index and middle finger and shortening of the...
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