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Toxicity of crude and detoxified Tityus serrulatus venom in anti-venom-producing sheep

Ferreira M, Duarte CG, Oliveira M, Castro KL, Teixeira M, Reis LP, Zambrano J, Kalapothakis E, Michel AF, Soto-Blanco B, Chávez-Olórtegui C, Melo MM

Specific anti-venom used to treat scorpion envenomation is usually obtained from horses after hyperimmunization with crude scorpion venom. However, immunized animals often become ill because of the toxic effects of...
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Tissue engineering of heart valves by recellularization of glutaraldehyde-fixed porcine valves using bone marrow-derived cells

Kim SS, Lim SH, Cho SW, Gwak SJ, Hong YS, Chang BC, Park MH, Song KW, Choi CY, Kim BS

  • KMID: 1094153
  • Exp Mol Med.
  • 2006 Jun;38(3):273-283.
To increase the biocompatibility and durability of glutaraldehyde (GA)-fixed valves, a biological coating with viable endothelial cells (ECs) has been proposed. However, stable EC layers have not been formed successfully...
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