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Cushing Syndrome Associated Myopathy: It Is Time for a Change

Reincke M

Cushing syndrome is the result of excessive levels of glucocorticoids. Endogenous Cushing syndrome is rare with an incidence of two to three cases per million per year. Clinically, the presentation...
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Update on Glucocorticoid Induced Osteoporosis

Cho SK, Sung YK

Glucocorticoids are used to treat many autoimmune and inflammatory diseases. However, an adverse systemic effect is a deleterious effect on bone, which may lead to glucocorticoid-induced osteoporosis, characterized by a...
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Current advances in the treatment of autoimmune-associated interstitial lung diseases

Lee S, Lee JH

Autoimmune-associated interstitial lung disease (ILD) is a widespread and clinically significant form of autoimmune diseases. ILD can be present in most type of autoimmune diseases. Scleroderma, Sjogren syndrome, rheumatoid arthritis,...
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Prednisolone-induced diabetes mellitus without pancreatic islet pathology in a dog

Yun T, Kim H, Koo Y, Chang D, Kang BT, Yang MP

A one-year-old, intact male Maltese was referred with dehydration, anorexia, and marked hyperglycemia. The dog had been managed due to meningoencephalitis of unknown etiology (MUE) for three months. The dog...
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Novel function of adrenocorticotropic hormone in the stimulation of vascular endothelial growth factor release in healthy children and adolescents: a proof-of-concept study

Heksch R, Bowden S, Hoffman R

Purpose: To assess the effect of adrenocorticotropic hormone (ACTH) on plasma vascular endothelial growth factor (VEGF) levels in healthy children and adolescents and to inform future work on the effects...
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Safety of epidural steroids: a review

Lee MS, Moon HS

Spine disease is one of the most common musculoskeletal diseases, especially in an aging society. An epidural steroid injection (ESI) is a highly effective treatment that can be used to...
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Perioperative glucocorticoid management based on current evidence

Seo KH

Glucocorticoid preparations, adreno-cortical steroids, with strong anti-inflammatory and immunosuppressive effects, are widely used for treating various diseases. The number of patients exposed to steroid therapy prior to surgery is increasing....
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Treatment Response to Idiopathic Retroperitoneal Fibrosis-associated Hydronephrosis With a Focus on IgG4/IgG3 Serum Concentration Ratio

Choi SJ, Oh JS, Hong S, Lee CK, Yoo B, Hong B, Kim YG

Objective. Hydronephrosis, a common complication of idiopathic retroperitoneal fibrosis (iRPF), may lead to poor renal outcomes unless resolved in a timely manner. IgG4-related diseases characterized by elevated serum IgG4 levels...
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Effects of Systemic Glucocorticoid Use on Fracture Risk: A Population-Based Study

Koh JW, Kim J, Cho H, Ha YC, Kim TY, Lee YK, Kim HY, Jang S

Background: Long-term glucocorticoid use increases fracture risk by reducing bone mass. This study evaluated the relationship between hip and vertebral fractures and the total amount of systematic glucocorticoid use. Methods: We...
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Association between perioperative glucocorticoids and cancer metastasis and survival in patients undergoing radical cystectomy for urothelial carcinoma of the bladder: A singlecenter retrospective study

Mao S, Wu Y, Wang R, Guo Y, Yuan J, Zhang W, Zhang J, Yan Y, Yao X

Purpose: Perioperative glucocorticoids have the potential to increase the risk of tumor metastasis. However, the relationship between perioperative glucocorticoids and oncologic outcomes remains controversial. The present study was undertaken to...
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Intravenous Glucocorticoid Treatment for Korean Graves' Ophthalmopathy Patients

Ahn HY, Lee JK

Background: High-dose intravenous steroids are the first-line treatment for patients with moderate-to-severe and active Graves' ophthalmopathy (GO). We aimed to investigate the response rate of methylprednisolone (MPD) treatment among Korean...
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Management of glucocorticoid-related osteoporotic vertebral fracture

Wong SPY, Mok CC

The vertebral column is the most common site of osteoporotic fractures in long-term users of glucocorticoids. Vertebral fracture leads to significant morbidities such as unrelenting pain, spinal deformities and reduced...
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Prescription of Systemic Steroids for Acute Respiratory Infections in Korean Outpatient Settings: Overall Patterns and Effects of the Prescription Appropriateness Evaluation Policy

Kim T, Do YK

Objectives: The objective of this study was to identify individual and institutional factors associated with the prescription of systemic steroids in patients with acute respiratory infections and to investigate the...
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Intervention Thresholds for Treatment in Patients with Glucocorticoid-Induced Osteoporosis: Systematic Review of Guidelines

Lee TH, Song YJ, Kim H, Sung YK, Cho SK

Background: In this study, we aimed to evaluate and compare the treatment indication for patients with glucocorticoid-induced osteoporosis (GIOP) in various clinical practice guidelines. Methods: We searched for potentially relevant studies...
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Comparison of Corticosteroids by 3 Approaches to the Treatment of Chronic Rhinosinusitis With Nasal Polyps

Zhang Y, Lou H, Wang Y, Li Y, Zhang L, Wang C

PURPOSE: Corticosteroids are regarded as the mainstay of medical treatment of eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). To date, a head-to-head comparison of the efficacy and safety of glucocorticoid...
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Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report

Park HJ, Park SH, Kim JH, Kim YH

Idiopathic granulomatous hypophysitis (IGH), a rare disease, requires differentiation from more common mass lesions of the sella such as pituitary adenoma, craniopharyngioma, Rathke's cleft cyst, or pituitary tuberculoma. IGH usually...
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A Case of Primary Central Nervous System Vasculitis That Worsened Despite Early Corticosteroid Therapy

Yoon SY, Park KS, Park SH, Park JY

Primary central nervous system vasculitis (PCNSV) is rare, and the diagnosis is difficult to make because of its variable radiologic expressions. Early corticosteroid therapy often is effective. Herein we report...
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Steroid Non-responsive Hashimoto's Encephalopathy Improved by Rituximab

Jang SH, Moon HJ, Cho YW

Hashimoto's encephalopathy is a rare autoimmune disease, with symptoms of encephalopathy and high titers of serum anti-thyroid antibodies. Current diagnostic criteria include corticosteroid responsiveness, but in some cases, they are...
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Korean Guideline for the Prevention and Treatment of Glucocorticoid-induced Osteoporosis

Park SY, Gong HS, Kim KM, Kim D, Kim HY, Jeon CH, Ju JH, Lee SS, Park DA, Sung YK, Kim SW

BACKGROUND: To develop guidelines and recommendations to prevent and treat glucocorticoid (GC)-induced osteoporosis (GIOP) in Korea. METHODS: The Korean Society for Bone and Mineral Research and the Korean College of Rheumatology...
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Korean Guideline for the Prevention and Treatment of Glucocorticoid-induced Osteoporosis

Park SY, Gong HS, Kim KM, Kim D, Kim H, Jeon CH, Ju JH, Lee SS, Park DA, Sung YK, Kim SW

OBJECTIVE: To develop guidelines and recommendations to prevent and treat glucocorticoid-induced osteoporosis (GIOP) in Korea. METHODS: The Korean Society for Bone and Mineral Research and the Korean College of Rheumatology developed...
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