- Pancreatic alpha-Cell Dysfunction in Type 2 Diabetes: Old Kids on the Block
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Moon JS, Won KC
- KMID: 2280650
- Diabetes Metab J.
- 2015 Feb;39(1):1-9.
- doi: 10.4093/dmj.2015.39.1.1
Type 2 diabetes (T2D) has been known as 'bi-hormonal disorder' since decades ago, the role of glucagon from alpha-cell has languished whereas beta-cell taking center stage. Recently, numerous findings indicate... -
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- A Case of Alpha-cell Nesidioblastosis and Hyperplasia with Multiple Glucagon-producing Endocrine Cell Tumor of the Pancreas
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Kang H, Kim S, Lim TS, Lee HW, Choi H, Kang CM, Kim HG, Bang S
- KMID: 1791884
- Korean J Gastroenterol.
- 2014 Apr;63(4):253-257.
- doi: 10.4166/kjg.2014.63.4.253
Nesidioblastosis is a term used to describe pathologic overgrowth of pancreatic islet cells. It also means maldistribution of islet cells within the ductules of exocrine pancreas. Generally, nesidioblastosis occurs in... -
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- Toll-like receptor 4 on islet beta cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes
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Li M, Song L, Gao X, Chang W, Qin X
- KMID: 1365903
- Exp Mol Med.
- 2012 Apr;44(4):260-267.
- doi: 10.3858/emm.2012.44.4.021
Type 1 diabetes mellitus is caused by the autoimmune destruction of beta cells within the islets. In recent years, innate immunity has been proposed to play a key role in... -
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