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Circulating factors in sera or peripheral blood mononuclear cells in patients with membranous nephropathy or diabetic nephropathy

Ihm CG, Park JK, Hong SP, Lee TW, Cho BS, Kim MJ

In order to investigate the status of some circulating factors in nephrotic syndrome, we examined the secretion of monocyte chemotactic peptide (MCP)-1, tumor necrosis factor (TNF) alpha or fibronectin...
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Role of mononuclear cells of IgA nephropathy on ICAM-1 expression in mesangial cells

Lee TW, Park JK, Ahn JH, Ihm CG, Kim MJ

  • KMID: 759058
  • Korean J Intern Med.
  • 1998 Feb;13(1):27-32.
OBJECTIVES: To investigate the possible role of mononuclear cells and their products in the pathogenesis of IgA nephropathy, in vitro expression of ICAM-1 on cultured mouse mesangial cell (MC) was...
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The effect of lovastatin on proliferation of cultured rat mesangial and aortic smooth muscle cells

Choi KH, Kang SW, Lee SW, Lee HY, Han DS, Kang BS

In order to investigate the anti-proliferative effect of 3-hydroxy-3-methylglutaryl coenzyme. A reductase inhibitor, we evaluated the effects of lovastatin on DNA replication and the proliferation of rat mesangial and aortic...
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The Protective Effects of Green Tea Extract against L-arginine Toxicity to Cultured Human Mesangial Cells

Shin BC, Ryu HH, Chung JH, Lee BR, Kim HL

The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated...
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Rapamycin Inhibits Platelet-Derived Growth Factor- Induced Collagen, but Not Fibronectin, Synthesis in Rat Mesangial Cells

Kim MS, Park J, Ha H, Kim YS, Kang SW, Jeong HJ, Kang DH, Yang CW

Rapamycin, a macrocyclic lactone, is effective in reducing the incidence of acute rejection after renal transplantation. The inhibitory effects of rapamycin on lymphocyte proliferation and the molecular mechanisms that were...
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Effects of High Glucose on Interleukin-6 Production in Human Mesangial Cells

Ihm CG, Park JK, Kim HJ, Lee TW, Cha DR

Interleukin (IL)-6 is an autocrine growth factor for mesangial cells. It is not known whether high glucose influences IL-6 production in mesangial cells. Angiotensin II (AGII) is involved in the...
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