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Electron microscopic study of the cases of minimal change nephrotic syndrome with mesangial IgA deposition

Jeong HJ, Jung SH, Choi IJ

Twenty-five cases of minimal change nephrotic syndrome(minimal change disease, MCD) with mesangial IgA deposition were evaluated electron microscopically. The thickness of the glomerular basement membrane(GBM) was 3875 +/- 1271 A...
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The Inhibitory Effect of siRNAs on The High Glucose-Induced Overexpression of TGF-beta1 in Mesangial Cells

Noh HJ, Kim HC, Lee SS, Kang YN, Chae YM, Park KK

Diabetic nephropathy is characterized by an expansion of the glomerular mesangium, caused by mesangial cell proliferation and an excessive accumulation of extracellar matrix (ECM) proteins, which eventually leading to glomerulosclerosis....
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