- Effect of IgA Aggregates on Transforming Growth Factor-beta1 Production in Human Mesangial Cells and the Intraglomerular Expression of Transforming Growth Factor-beta1 in Patients with IgA Nephropathy
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Han SY, Ihm CG, Cha DR, Kang YS, Han KH, Kim HK, Han JY
- KMID: 1776695
- Korean J Intern Med.
- 2005 Mar;20(1):40-47.
- doi: 10.3904/kjim.2005.20.1.40
BACKGROUND: Transforming growth factor-beta (TGF-beta) stimulates renal fibrosis in various renal diseases including IgA nephropathy. METHODS: We examined whether immunoglobulin A (IgA) stimulated TGF-beta1 synthesis in human mesangial cells (MCs),... -
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