- Transforming growth factor-beta and the glomerular filtration barrier
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Ghayur A, Margetts P
- KMID: 2224313
- Kidney Res Clin Pract.
- 2013 Mar;32(1):3-10.
The increasing burden of chronic kidney disease worldwide and recent advancements in the understanding of pathologic events leading to kidney injury have opened up new potential avenues for therapies to... -
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- Genetic Basis of Steroid Resistant Nephrotic Syndrome
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Park E
- KMID: 2464932
- Child Kidney Dis.
- 2019 Oct;23(2):86-92.
- doi: 10.3339/jkspn.2019.23.2.86
Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for... -
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- Current concepts of the podocyte in nephrotic syndrome
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Ding WY, Saleem MA
- KMID: 1441573
- Kidney Res Clin Pract.
- 2012 Jun;31(2):87-93.
Nephrotic syndrome is a disorder of the glomerular filtration barrier, and central to the filtration mechanism of the glomerular filtration barrier is the podocyte. We are starting to better understand... -
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- Effects of Angiotensin II on Glomerular Epithelial Cells Permeability Model; Role of Oxidative Stress
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Song CJ, Ha TS, Lee HS, Yoon OJ
- KMID: 2079396
- Korean J Nephrol.
- 2004 May;23(3):396-404.
BACKGROUND: Glomerular injury induced by angiotensin II (Ang II) may arise from its hemodynamic or non-hemodynamic actions including oxidative stress, or from such effects of Ang II acting in concert.... -
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- Urine synaptopodin excretion is an important marker of glomerular disease progression
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Kwon SK, Kim SJ, Kim HY
- KMID: 2350983
- Korean J Intern Med.
- 2016 Sep;31(5):938-943.
- doi: 10.3904/kjim.2015.226
BACKGROUND/AIMS: Podocytes play an important role in maintaining the glomerular filtration barrier and in formation of the slit diaphragm. Podocyte loss is associated with chronic kidney disease progression, but it... -
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- GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes
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Kim SH, Kim HJ, Kim CW
- KMID: 2361520
- Exp Mol Med.
- 2016 May;48(5):e233.
- doi: 10.1038/emm.2016.28
Podocyte foot processes are interdigitated to form the slit diaphragm and are crucial for the glomerular filtration barrier. Glucocorticoid-induced transcript 1 (GLCCI1) is transcriptionally regulated, but its signaling pathway in... -
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- Angiopoietins in Diabetic Nephropathy
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Lee EY, Gil HW, Yang JO, Koh JH, Chung CH, Hong SY
- KMID: 2079686
- Korean J Nephrol.
- 2007 May;26(3):311-319.
PURPOSE: It has been reported that angiopoietins and Tie-2 receptor play an important role in the maintenance of glomerular filtration barrier in various glomerulonephritis models. We studied the role of... -
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- Interleukin-13 Increases Podocyte Apoptosis in Cultured Human Podocytes
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Lee KH, Oh JY, Seong SB, Ha TS, Shin JI
- KMID: 2435351
- Child Kidney Dis.
- 2018 Apr;22(1):22-27.
- doi: 10.3339/jkspn.2018.22.1.22
PURPOSE: Podocytes are important architectures that maintain the crucial roles of glomerular filtration barrier functions. Despite this structural importance, however, the mechanisms of the changes in podocytes that can be... -
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- P-Cadherin is Decreased in Glucose-Stimulated Podocytes and in Experimental Diabetic Nephropathy
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Ryu DR, Xu ZG, Yoo TH, Chang JH, Jung DS, Lee SH, Kim JJ, Choi KH, Lee HY, Han DS, Kang SW
- KMID: 2079302
- Korean J Nephrol.
- 2003 Sep;22(5):494-503.
BACKGROUND: Proteinuria is a cardinal feature of glomerular disease including diabetic nephropathy, and glomerular filtration barrier is considered as a filter restricting protein excretion in urine. We tested whether the... -
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- Pathogenesis of minimal change nephrotic syndrome: an immunological concept
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Kim SH, Park SJ, Han KH, Kronbichler A, Saleem MA, Oh J, Lim BJ, Shin JI
- KMID: 2164983
- Korean J Pediatr.
- 2016 May;59(5):205-211.
- doi: 10.3345/kjp.2016.59.5.205
Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia. Minimal change nephrotic syndrome (MCNS) is the most common form of INS in children. The pathogenesis of... -
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- Expression of Nephrin in Puromycin Aminonucleoside Nephrosis in Rat
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Lee YK, Kwon TG, Kim DJ, Kim MK, Yoon SJ, Lee HH, Kim JA, Huh WS, Kim YG, Oh HY
- KMID: 2254432
- Korean J Nephrol.
- 2002 May;21(3):382-390.
BACKGROUND: Nephrin, a recently identified protein, could be a slit diaphragm component and it has been suggested to play a crucial role in maintaining the glomerular filtration barrier. It has... -
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- Changes of ZO-1 Expression in Diabetic Rat Glomeruli and Cultured Mouse Podocyte Under High Glucose Conditions and the Effect of Angiotensin II Type 1 Receptor Blocker
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Kim BS, Xu ZG, Park HC, Kang SW, Choi KH, Ha SK, Lee HY, Han DS
- KMID: 2079346
- Korean J Nephrol.
- 2003 Nov;22(6):632-644.
BACKGROUND: Diabetic nephropathy (DN) is clinically characterized by persistent proteinuria. The underlying pathologic changes responsible for the nephropathy are the loss of size selective and/or charge selective properties of the... -
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