- The Effect of Protein Kinase C Pretreatment on Gliotoxin Induced Apoptosis in H9c2 Cells
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Her JM, Oh JM, Park RK, So HS, Mun YJ, Choi MK, Lee GS, Chung YT, Park OK
- KMID: 1578399
- Korean J Phys Anthropol.
- 2000 Mar;13(1):119-128.
Aspergillus funigatus and other pathogenic fungi synthesize a toxic epidithi- odiopiperzine (ETP) metabolite called gliotoxin. Gliotoxin is an epidithiodiopiperzine compound which can both react with sulfhydryl groups and form hydrogen... -
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- Gliotoxin induces the Apoptosis in HL-60 Cells
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Chung HT, Park RK, Choi YK, Lee SR, Kim YH, Cho KH, Jang YW
- KMID: 1557245
- Korean J Immunol.
- 1998 Dec;20(4):397-403.
Many fungi including Penicillium, Aspergillus, Gliocladium, and Thermoascus produce an epipolythiodioxopiperazine class of fungal metabolite, gliotoxin, which contirbutes the pathogenesis of fungal infection as an immunomodulator and cytotoxic agent. This... -
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- The Protective Mechanism of Zinc in Fungal Metabolte Gliotoxin - induced Apoptosis
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Park JS, So HS, Kim MS, Jung BH, Choi IJ, Jin GH, Jin SH, Kim NS, Cho KH, Park R
- KMID: 2099311
- J Korean Soc Microbiol.
- 1999 Dec;34(6):501-512.
Gliotoxin, a fungal metabolite, is one of the epipolythiodioxopiperazine classes and has a variety of effects including imrnunomodulatory and apoptotic agents. This study is designed to evaluate the effect of... -
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- Gliotoxin is Antibacterial to Drug-resistant Piscine Pathogens
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Feng H, Liu S, Su M, Kim EL, Hong J, Jung JH
- KMID: 2432415
- Nat Prod Sci.
- 2018 Dec;24(4):225-228.
- doi: 10.20307/nps.2018.24.4.225
By activity-guided fractionation, gliotoxin was isolated as an antibacterial metabolite of the fungus Penicillium decumbens which was derived from the jellyfish Nemopilema nomurai. Gliotoxin was further evaluated for antibacterial activity... -
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- Protective Effect of PKC Affecting Gliotoxin-induced Cytotoxicity in Rat Smooth Muscle Cells
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Bang HJ, Kim JO, Oh JT, Lee HS, Cheong YK, Hur JM, Oh JM, Choi MK, Park ST, Chung YT
- KMID: 2092806
- Korean J Anat.
- 2003 Oct;36(5):371-380.
Aspergillus funigatus and other pathogenic fungi synthesize a toxic epidithi-odiopiperzine (ETP) metabolite, namely gliotoxin. Gliotoxin commonly react with sulfhydryl groups, and then, forms hydrogen peroxide. These fungal toxins induce apoptotic... -
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- Gliotoxin Protects Against TNBS-induced Colitis Via Down-regulation of NF B Activation
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Kim SJ, Choi DH, Chung YT
- KMID: 2224511
- Korean J Anat.
- 2004 Jun;37(3):309-315.
During inflammation of the colon, cells of the gut mucosa express numerous inflammatory mediators including interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), and interleukin-1beta(IL-1beta). These cytokines have been implicated as contributing... -
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- Regulation of Development in Aspergillus nidulans and Aspergillus fumigatus
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Yu JH
- KMID: 2312586
- Mycobiology.
- 2010 Dec;38(4):229-237.
Members of the genus Aspergillus are the most common fungi and all reproduce asexually by forming long chains of conidiospores (or conidia). The impact of various Aspergillus species on humans... -
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- The Factors Affecting Transplanted Hepatocytes Repopulation in Rats with Liver Fibrosis
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Lee SW, Min SO, Choi SB, Kim KS
- KMID: 1469755
- Korean J Hepatobiliary Pancreat Surg.
- 2009 Dec;13(4):189-197.
PURPOSE: Cell therapy for various diseases has gained wide acceptance. Because most patients with chronic liver failure have mild-to-severe liver cirrhosis, there are many limitations to clinical applications. We analyzed... -
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