- Brain Tumor Stem Cells as Therapeutic Targets in Models of Glioma
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Laks DR, Visnyei K, Kornblum H
- KMID: 1071412
- Yonsei Med J.
- 2010 Sep;51(5):633-640.
- doi: 10.3349/ymj.2010.51.5.633
At this time, brain tumor stem cells remain a controversial hypothesis while malignant brain tumors continue to present a dire prognosis of severe morbidity and mortality. Yet, brain tumor stem... -
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- Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
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Han S, Huh J, Kim W, Jeong S, Min DS, Jung Y
- KMID: 2155391
- Exp Mol Med.
- 2014 Dec;46(12):e126.
- doi: 10.1038/emm.2014.86
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is... -
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