- 5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas
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Park SH, Jung KC, Ro JY, Kang GH, Khang SK
- KMID: 965879
- J Korean Med Sci.
- 2000 Oct;15(5):555-559.
- doi: 10.3346/jkms.2000.15.5.555
Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed... -
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