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The N-terminal 1-16 peptide derived in vivo from protein seminal vesicle protein IV modulates alpha-thrombin activity: potential clinical implications

Lepretti M, Costantini S, Ammirato G, Giuberti G, Caraglia M, Facchiano , Metafora S, Stiuso P

We have previously shown that seminal vesicle protein IV (SV-IV) and its 1-70 N-terminal fragment have anti-inflammatory activity and modulate anti-thrombin III (AT) activity. Moreover, mass spectrometry analysis of purified...
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Alternative therapy of earth elements increases the chondroprotective effects of chondroitin sulfate in mice

Caraglia M, Beninati S, Giuberti G, D'Alessandro A, Lentini A, Abbruzzese A, Bove G, Landolfi F, Rossi F, Lampa E, Costantino M

  • KMID: 1089457
  • Exp Mol Med.
  • 2005 Oct;37(5):476-481.
The administration of mineral sulphur water is an alternative experimental approach for the treatment of rheumatic diseases, such as osteoarthritis (OA), that cause the degeneration of bone and cartilage and...
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