- Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: A Bridge between Functional Organic Dichotomy
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Ghoshal UC, Shukla R, Ghoshal U
- KMID: 2412185
- Gut Liver.
- 2017 Mar;11(2):196-208.
- doi: 10.5009/gnl16126
The pathogenesis of irritable bowel syndrome (IBS), once thought to be largely psychogenic in origin, is now understood to be multifactorial. One of the reasons for this paradigm shift is... -
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- Irritable Bowel Syndrome, Particularly the Constipation-Predominant Form, Involves an Increase in Methanobrevibacter smithii, Which Is Associated with Higher Methane Production
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Ghoshal U, Shukla R, Srivastava D, Ghoshal UC
- KMID: 2412099
- Gut Liver.
- 2016 Nov;10(6):932-938.
- doi: 10.5009/gnl15588
BACKGROUND/AIMS: Because Methanobrevibacter smithii produces methane, delaying gut transit, we evaluated M. smithii loads in irritable bowel syndrome (IBS) patients and healthy controls (HC). METHODS: Quantitative real-time polymerase chain reaction for... -
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- Expression of Toll-like Receptors, Pro-, and Anti-inflammatory Cytokines in Relation to Gut Microbiota in Irritable Bowel Syndrome: The Evidence for Its Micro-organic Basis
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Shukla R, Ghoshal U, Ranjan P, Ghoshal UC
- KMID: 2422853
- J Neurogastroenterol Motil.
- 2018 Oct;24(4):628-642.
- doi: 10.5056/jnm18130
BACKGROUND/AIMS: A Subset of patients with irritable bowel syndrome (IBS) may have mild inflammation due to immune activation. Toll-like receptors (TLRs) and cytokines may cause intestinal inflammation. We studied their... -
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