- Molecular docking Study of Nuciferine as a Tyrosinase Inhibitor and Its Therapeutic Potential for Hyperpigmentation
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Veerichetty V, Saravanabavan I
- KMID: 2547077
- Genomics Inform.
- 2023 Sep;21(3):e43.
- doi: 10.5808/gi.23054
Melanin is synthesized by tyrosinase to protect the skin from ultraviolet light. However, overproduction and accumulation of melanin can result in hyperpigmentation and skin melanoma. Tyrosinase inhibitors are commonly used... -
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- Identifying pathogenic variants related to systemic lupus erythematosus by integrating genomic databases and a bioinformatic approach
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Yudhani RD, Pakha DN, Suyatmi S, Irham LM
- KMID: 2547071
- Genomics Inform.
- 2023 Sep;21(3):e37.
- doi: 10.5808/gi.23002
Systemic lupus erythematosus (SLE) is an inflammatory-autoimmune disease with a complex multi-organ pathogenesis, and it is known to be associated with significant morbidity and mortality. Various genetic, immunological, endocrine, and... -
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- Lack of association between the VEGFA gene polymorphisms and preterm birth in Korean women
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Shi Y, Kim HJ, Kim SY, Kim GE, Jin HJ
- KMID: 2547063
- Genomics Inform.
- 2023 Sep;21(3):e29.
- doi: 10.5808/gi.22064
Preterm birth (PTB), a pregnancy-related disease, is defined as a birth before 37 weeks of gestation. It is a major cause of maternal mortality and morbidity worldwide, and its incidence... -
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- M Protein from Dengue virus oligomerizes to pentameric channel protein: in silico analysis study
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Zeba A, Sekar K, Ganjiwale A
- KMID: 2547075
- Genomics Inform.
- 2023 Sep;21(3):e41.
- doi: 10.5808/gi.23035
The Dengue virus M protein is a 75 amino acid polypeptide with two helical transmembranes (TM). The TM domain oligomerizes to form an ion channel, facilitating viral release from the... -
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- Structural dynamics insights into the M306L, M306V, and D1024N mutations in Mycobacterium tuberculosis inducing resistance to ethambutol
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Maladan Y, Safari D, Parikesit AA
- KMID: 2547066
- Genomics Inform.
- 2023 Sep;21(3):e32.
- doi: 10.5808/gi.23019
Resistance to anti-tuberculosis drugs, especially ethambutol (EMB), has been widely reported worldwide. EMB resistance is caused by mutations in the embB gene, which encodes the arabinosyl transferase enzyme. This study... -
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- Whole genome sequence analyses of thermotolerant Bacillus sp. isolates from food
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Sornchuer P, Saninjuk K, Tingpej P
- KMID: 2547069
- Genomics Inform.
- 2023 Sep;21(3):e35.
- doi: 10.5808/gi.23030
The Bacillus cereus group, also known as B. cereus sensu lato (B. cereus s.l.), is composed of various Bacillus species, some of which can cause diarrheal or emetic food poisoning.... -
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- A genome‑wide approach to the systematic and comprehensive analysis of LIM gene family in sorghum (Sorghum bicolor L.)
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Sarkar MAR, Sarkar S, Islam MS, Zohra FT, Rahman SM
- KMID: 2547070
- Genomics Inform.
- 2023 Sep;21(3):e36.
- doi: 10.5808/gi.23007
The LIM domain-containing proteins are dominantly found in plants and play a significant role in various biological processes such as gene transcription as well as actin cytoskeletal organization. Nevertheless, genome-wide... -
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- Bayesian bi-level variable selection for genome-wide survival study
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Lee E, Ibrahim JG, Zhu H, for the Alzheimer’s Disease Neuroimaging Initiative
- KMID: 2547062
- Genomics Inform.
- 2023 Sep;21(3):e28.
- doi: 10.5808/gi.23047
Mild cognitive impairment (MCI) is a clinical syndrome characterized by the onset and evolution of cognitive impairments, often considered a transitional stage to Alzheimer’s disease (AD). The genetic traits of... -
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- Association of CAPN10 gene (rs3842570) polymorphism with the type 2 diabetes mellitus among the population of Noakhali region in Bangladesh: a case-control study
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Sultana M, Islam MM, Hossain MM, Rahman MA, Das SC, Barman DN, Mitu FS, Gupta SD
- KMID: 2547067
- Genomics Inform.
- 2023 Sep;21(3):e33.
- doi: 10.5808/gi.23023
Type 2 diabetes mellitus (T2DM) is a multifactorial, polygenic, and metabolically complicated disease. A large number of genes are responsible for the biogenesis of T2DM and calpain10 (CAPN10) is one... -
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- In-silico and structure-based assessment to evaluate pathogenicity of missense mutations associated with non-small cell lung cancer identified in the Eph-ephrin class of proteins
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Chakraborty S, Baruah R, Mishra N, Varma AK
- KMID: 2547064
- Genomics Inform.
- 2023 Sep;21(3):e30.
- doi: 10.5808/gi.22069
Ephs belong to the largest family of receptor tyrosine kinase and are highly conserved both sequentially and structurally. The structural organization of Eph is similar to other receptor tyrosine kinases;... -
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- Identification of novel potential drugs and miRNAs biomarkers in lung cancer based on gene co-expression network analysis
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Hajipour S, Hosseini SM, Irani S, Tavallaie M
- KMID: 2547072
- Genomics Inform.
- 2023 Sep;21(3):e38.
- doi: 10.5808/gi.23039
Non–small cell lung cancer (NSCLC) is an important cause of cancer-associated deaths worldwide. Therefore, the exact molecular mechanisms of NSCLC are unidentified. The present investigation aims to identify the miRNAs... -
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- Multi-epitope vaccine against drug-resistant strains of Mycobacterium tuberculosis: a proteome-wide subtraction and immunoinformatics approach
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Khan MT, Mahmud A, Islam MM, Sumaia MSN, Rahim Z, Islam K, Iqbal A
- KMID: 2547076
- Genomics Inform.
- 2023 Sep;21(3):e42.
- doi: 10.5808/gi.23021
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, one of the most deadly infections in humans. The emergence of multidrug-resistant and extensively drug-resistant Mtb strains presents a global challenge.... -
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- Whole genomic sequencing of Staphylococcus aureus strain RMI-014804 isolated from pulmonary patient sputum via next-generation sequencing technology
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Wisal A, Ullah A, Anwar W, Morel CM, Hassan SS
- KMID: 2547068
- Genomics Inform.
- 2023 Sep;21(3):e34.
- doi: 10.5808/gi.23024
Nosocomial infections, commonly referred to as healthcare-associated infections, are illnesses that patients get while hospitalized and are typically either not yet manifest or may develop. One of the most prevalent... -
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- Identification of druggable genes for multiple myeloma based on genomic information
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Satria RD, Irham LM, Adikusuma W, Puspitaningrum AN, Afief AR, Khair RE, Septama AW
- KMID: 2547065
- Genomics Inform.
- 2023 Sep;21(3):e31.
- doi: 10.5808/gi.23011
Multiple myeloma (MM) is a hematological malignancy. It is widely believed that genetic factors play a significant role in the development of MM, as investigated in numerous studies. However, the... -
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- A streamlined pipeline based on HmmUFOtu for microbial community profiling using 16S rRNA amplicon sequencing
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Kim H, Kim J, Choi JW, Ahn KS, Park DI, Kim S
- KMID: 2547074
- Genomics Inform.
- 2023 Sep;21(3):e40.
- doi: 10.5808/gi.23044
Microbial community profiling using 16S rRNA amplicon sequencing allows for taxonomic characterization of diverse microorganisms. While amplicon sequence variant (ASV) methods are increasingly favored for their fine-grained resolution of sequence... -
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- Overcoming taxonomic challenges in DNA barcoding for improvement of identification and preservation of clariid catfish species
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Chalermwong P, Panthum T, Wattanadilokcahtkun P, Ariyaraphong N, Thong T, Srikampa P, Singchat W, Ahmad SF, Noito K, Rasoarahona R, Lisachov A, Ali H, Kraichak E, Muangmai N, Chatchaiphan S, Sriphairoj K, Hatachote S, Chaiyes A, Jantasuriyarat C, Chailertlit V, Suksavate W, Sonongbua J, Srimai W, Payungporn S, Han K, Antunes A, Srisapoome P, Koga A, Duengkae P, Matsuda Y, Na-Nakorn U, Srikulnath K
- KMID: 2547073
- Genomics Inform.
- 2023 Sep;21(3):e39.
- doi: 10.5808/gi.23038
DNA barcoding without assessing reliability and validity causes taxonomic errors of species identification, which is responsible for disruptions of their conservation and aquaculture industry. Although DNA barcoding facilitates molecular identification... -
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