- Editor’s introduction to this issue (G&I 20:3, 2022)
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Park T
- KMID: 2535360
- Genomics Inform.
- 2022 Sep;20(3):e25.
- doi: 10.5808/gi.20.3.e1
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- Viral culture, genome characterization, and mutation analysis of human influenza A virus
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Mungmunpuntipantip R, Wiwanitkti V
- KMID: 2535372
- Genomics Inform.
- 2022 Sep;20(3):e37.
- doi: 10.5808/gi.22043
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- NBLAST: a graphical user interface-based two-way BLAST software with a dot plot viewer
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Choi BS, Choi SK, Kim NS, Choi IY
- KMID: 2535371
- Genomics Inform.
- 2022 Sep;20(3):e36.
- doi: 10.5808/gi.22053
BLAST, a basic bioinformatics tool for searching local sequence similarity, has been one of the most widely used bioinformatics programs since its introduction in 1990. Users generally use the web-based... -
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- The effect of missing levels of nesting in multilevel analysis
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Park S, Chung Y
- KMID: 2535369
- Genomics Inform.
- 2022 Sep;20(3):e34.
- doi: 10.5808/gi.22052
Multilevel analysis is an appropriate and powerful tool for analyzing hierarchical structure data widely applied from public health to genomic data. In practice, however, we may lose the information on... -
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- Whole-exome sequencing analysis in a case of primary congenital glaucoma due to the partial uniparental isodisomy
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Zavarzadeh PG, Bonyadi M, Abedi Z
- KMID: 2535363
- Genomics Inform.
- 2022 Sep;20(3):e28.
- doi: 10.5808/gi.21044
We described a clinical, laboratory, and genetic presentation of a pathogenic variant of the CYP1B1 gene through a report of a case of primary congenital glaucoma and a trio analysis... -
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- A systemic study on the vulnerability and fatality of prostate cancer patients towards COVID-19 through analysis of the TMPRSS2, CXCL10 and their co-expressed genes
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Raza MT, Mizan S
- KMID: 2535366
- Genomics Inform.
- 2022 Sep;20(3):e31.
- doi: 10.5808/gi.22012
A pandemic of respiratory disease named coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is reported prostate cancer patients are... -
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- Analysis of gene expression profiles to study malaria vaccine dose efficacy and immune response modulation
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Dey S, Kaur H, Mazumder M, Brodsky E
- KMID: 2535367
- Genomics Inform.
- 2022 Sep;20(3):e32.
- doi: 10.5808/gi.22049
Malaria is a life-threatening disease, and Africa is still one of the most affected endemic regions despite years of policy to limit infection and transmission rates. Further, studies into the... -
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- Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease
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Asmy VkSS, Natarajan J
- KMID: 2535361
- Genomics Inform.
- 2022 Sep;20(3):e26.
- doi: 10.5808/gi.22029
Diabetes and its related complications are associated with long term damage and failure of various organ systems. The microvascular complications of diabetes considered in this study are diabetic retinopathy, diabetic... -
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- Mining and analysis of microsatellites in human coronavirus genomes using the in-house built Java pipeline
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Umang , Bharti PK, Husai A
- KMID: 2535370
- Genomics Inform.
- 2022 Sep;20(3):e35.
- doi: 10.5808/gi.20033
Microsatellites or simple sequence repeats are motifs of 1 to 6 nucleotides in length present in both coding and non-coding regions of DNA. These are found widely distributed in the... -
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- Two novel mutations in ALDH18A1 and SPG11 gene found by whole-exome sequencing in spastic paraplegia disease patients in Iran
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Komachali SR, Siahpoosh Z, Salehi M
- KMID: 2535365
- Genomics Inform.
- 2022 Sep;20(3):e30.
- doi: 10.5808/gi.22030
Hereditary spastic paraplegia is a not common inherited neurological disorder with heterogeneous clinical expressions. ALDH18A1 (located on 10q24.1) gene-related spastic paraplegias (SPG9A and SPG9B) are rare metabolic disorders caused by... -
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- Computer-aided drug design of Azadirachta indica compounds against nervous necrosis virus by targeting grouper heat shock cognate protein 70 (GHSC70): quantum mechanics calculations and molecular dynamic simulation approaches
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Islam SI, Saloa S, Mahfuj S, Islam MJ, Mou MJ
- KMID: 2535368
- Genomics Inform.
- 2022 Sep;20(3):e33.
- doi: 10.5808/gi.21063
Nervous necrosis virus (NNV) is a deadly infectious disease that affects several fish species. It has been found that the NNV utilizes grouper heat shock cognate protein 70 (GHSC70) to... -
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- Pathogenesis and prognosis of primary oral squamous cell carcinoma based on microRNAs target genes: a systems biology approach
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Taherkhani A, Dehto SS, Jamshidi S, Shojaei S
- KMID: 2535362
- Genomics Inform.
- 2022 Sep;20(3):e27.
- doi: 10.5808/gi.22038
Oral squamous cell carcinoma (OSCC) is the most prevalent head and neck malignancy, with frequent cervical lymph-node metastasis, leading to a poor prognosis in OSCC patients. The present study aimed... -
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- The UGT1A9*22 genotype identifies a high-risk group for irinotecan toxicity among gastric cancer patients
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Lee Ck, Chon HJ, Kwon WS, Ban HJ, Kim SC, Kim H, Jeung HC, Chung J, Rha SY
- KMID: 2535364
- Genomics Inform.
- 2022 Sep;20(3):e29.
- doi: 10.5808/gi.22051
Several studies have shown associations between irinotecan toxicity and UGT1A genetic variations in colorectal and lung cancer, but only limited data are available for gastric cancer patients. We evaluated the... -
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