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TRAPR: R Package for Statistical Analysis and Visualization of RNA-Seq Data

Lim JH, Lee SY, Kim JH

High-throughput transcriptome sequencing, also known as RNA sequencing (RNA-Seq), is a standard technology for measuring gene expression with unprecedented accuracy. Numerous bioconductor packages have been developed for the statistical analysis...
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Circulating Tumor DNA in a Breast Cancer Patient's Plasma Represents Driver Alterations in the Tumor Tissue

Lee J, Cho SM, Kim MS, Lee SH, Chung YJ, Jung SH

Tumor tissues from biopsies or surgery are major sources for the next generation sequencing (NGS) study, but these procedures are invasive and have limitation to overcome intratumor heterogeneity. Recent studies...
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Comparative Analysis of Predicted Gene Expression among Crenarchaeal Genomes

Das S, Chottopadhyay B, Sahoo S

Research into new methods for identifying highly expressed genes in anonymous genome sequences has been going on for more than 15 years. We presented here an alternative approach based on...
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DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals

Rhee JK, Lee JH, Yang HK, Kim TM, Yoon KH

Obesity is a highly prevalent, chronic disorder that has been increasing in incidence in young patients. Both epigenetic and genetic aberrations may play a role in the pathogenesis of obesity....
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Use of Graph Database for the Integration of Heterogeneous Biological Data

Yoon BH, Kim SK, Kim SY

Understanding complex relationships among heterogeneous biological data is one of the fundamental goals in biology. In most cases, diverse biological data are stored in relational databases, such as MySQL and...
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A ChIP-Seq Data Analysis Pipeline Based on Bioconductor Packages

Park SJ, Kim JH, Yoon BH, Kim SY

Nowadays, huge volumes of chromatin immunoprecipitation-sequencing (ChIP-Seq) data are generated to increase the knowledge on DNA-protein interactions in the cell, and accordingly, many tools have been developed for ChIP-Seq analysis....
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Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation

Lee H, Park YM, We YM, Han DJ, Seo JW, Moon H, Lee YH, Kim YG, Moon JY, Lee SH, Lee JK

Early detection and proper management of kidney rejection are crucial for the long-term health of a transplant recipient. Recipients are normally monitored by serum creatinine measurement and sometimes with graft...
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Editor's Introduction to This Issue (G&I 15:1, 2017)

Chung YJ

No abstract available.
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