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In Silico Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18

Kumar S, Jena L, Sahoo M, Kakde M, Daf S, Varma AK

The leading cause of cancer mortality globally amongst the women is due to human papillomavirus (HPV) infection. There is need to explore anti-cancerous drugs against this life-threatening infection. Traditionally, different...
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In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139

Islam MS, Shahik SM, Sohel M, Patwary NI, Hasan MA

In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in...
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Elucidation of the Molecular Interaction between miRNAs and the HOXA9 Gene, Involved in Acute Myeloid Leukemia, by the Assistance of Argonaute Protein through a Computational Approach

Das RP, Konkimalla VB, Rath SN, Hansa J, Jagdeb M

Acute myeloid leukemia is a well characterized blood cancer in which the unnatural growth of immature white blood cell takes place, where several genes transcription is regulated by the micro...
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Genetic Architecture of Transcription and Chromatin Regulation

Kim K, Bang H, Lee K, Choi JK

DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic...
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Effect of Next-Generation Exome Sequencing Depth for Discovery of Diagnostic Variants

Kim K, Seong MW, Chung WH, Park SS, Leem S, Park W, Kim J, Lee K, Park RW, Kim N

Sequencing depth, which is directly related to the cost and time required for the generation, processing, and maintenance of next-generation sequencing data, is an important factor in the practical utilization...
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A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression

Lee YS

nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III)...
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Editor's Introduction to This Issue

Chung YJ

No abstract available.
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