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Editor's Introduction to This Issue

Chung YJ

No abstract available.
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Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5

Kim S, Lee JW

The epithelial-mesenchymal transition (EMT) is one mechanism by which cells with mesenchymal features can be generated and is a fundamental event in morphogenesis. Recently, invasion and metastasis of cancer cells...
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Next-Generation Sequencing and Epigenomics Research: A Hammer in Search of Nails

Sarda S, Hannenhalli S

After the initial enthusiasm of the human genome project, it became clear that without additional data pertaining to the epigenome, i.e., how the genome is marked at specific developmental periods,...
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Interactive Visualization for Patient-to-Patient Comparison

Nguyen QV, Nelmes G, Huang ML, Simoff S, Catchpoole D

A visual analysis approach and the developed supporting technology provide a comprehensive solution for analyzing large and complex integrated genomic and biomedical data. This paper presents a methodology that is...
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Identification of Ethnically Specific Genetic Variations in Pan-Asian Ethnos

Yang JO, Hwang S, Kim WY, Park SJ, Kim SC, Park K, Lee B, The HUGO Pan-Asian SNP Consortium

Asian populations contain a variety of ethnic groups that have ethnically specific genetic differences. Ethnic variants may be highly relevant in disease and human differentiation studies. Here, we identified ethnically...
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples

Kim H, Yoo WG, Park J, Kim H, Kang BC

Single-nucleotide polymorphisms (SNPs) have been emerging out of the efforts to research human diseases and ethnic disparities. A semantic network is needed for in-depth understanding of the impacts of SNPs,...
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