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CpG Islands Detector: a Window-based CpG Island Search Tool

Kim KB

  • KMID: 2166478
  • Genomics Inform.
  • 2010 Mar;8(1):58-61.
CpG is the pair of nucleotides C and G, appearing successively, in this order, along one DNA strand. It is known that due to biochemical considerations CpG is relatively rare...
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Effects of Mercuric Chloride on Gene Expression in NRK-52E Cells

Ahn JI, Baik SY, Ko MJ, Shin HJ, Chung HJ, Jeong HS

  • KMID: 2166477
  • Genomics Inform.
  • 2010 Mar;8(1):50-57.
Mercuric chloride, a model nephrotoxicant was used to elucidate time- and dose-dependent global gene expression changes associated with proximal tubular toxicity. Rat kidney cell lines NRK-52E cells were exposed for...
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Gene Expression Analysis for Statin-induced Cytotoxicity from Rat Primary Hepatocytes

Ko MJ, Ahn JI, Shin HJ, Kim HS, Chung HJ, Jeong HS

  • KMID: 2166476
  • Genomics Inform.
  • 2010 Mar;8(1):41-49.
Statins are competitive inhibitors of hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase and used most frequently to reduce plasma cholesterol levels and to decrease cardiovascular events. However, statins also have been...
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Classification of Biological Effect of 1,763 MHz Radiofrequency Radiation Based on Gene Expression Profiles

Im CN, Kim EH, Park AK, Park WY

  • KMID: 2166475
  • Genomics Inform.
  • 2010 Mar;8(1):34-40.
Radiofrequency (RF) radiation might induce the transcription of a certain set of genes as other physical stresses like ionizing radiation and UV. To observe transcriptional changes upon RF radiation, we...
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Genome-wide Response of Normal WI-38 Human Fibroblast Cells to 1,763 MHz Radiofrequency Radiation

Im CN, Kim EH, Park AK, Park WY

  • KMID: 2166474
  • Genomics Inform.
  • 2010 Mar;8(1):28-33.
Increased exposure of human to RF fields has raised concerns for its potential adverse effects on our health. To address the biological effects of RF radiation, we used genome wide...
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Replication of the Association between Copy Number Variation on 8p23.1 and Autism by Using ASD-specific BAC Array

Woo JH, Yang SJ, Yim SH, Hu HJ, Shin MJ, Oh EH, Kang HW, Park S, Chung YJ

  • KMID: 2166473
  • Genomics Inform.
  • 2010 Mar;8(1):19-27.
To discover genetic markers for autism spectrum disorder (ASD), we previously applied genome-wide BAC array comparative genomic hybridization (array-CGH) to 28 autistic patients and 62 normal controls in Korean population,...
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Putative Association of ITGB1 Haplotype with the Clearance of HBV Infection

Park TJ, Chun JY, Bae JS, Kim JY, Lee JS, Pasaje CF, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166472
  • Genomics Inform.
  • 2010 Mar;8(1):9-18.
Integrins are transmembrane receptor proteins that mediate cell-cell adhesion and cell-extracellular matrix (ECM) adhesion. The deregulation of cell-ECM adhesion and the abnormal expression of beta1 (beta1) integrins (ITGB1s) are involved...
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Association Analysis of SERPINB5 Polymorphisms with HBV Clearance and HCC Occurrence in a Korean Population

Kim JY, Park TJ, Lee JS, Chun JY, Bae JS, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166471
  • Genomics Inform.
  • 2010 Mar;8(1):1-8.
Serpin peptidase inhibitor, Clade B (ovalbumin), Member 5 (SERPINB5), also known as maspin, is a potent tumor suppressor gene. It has correlations with many tumor cells, from pancreas cancer to...
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