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A Simple GUI-based Sequencing Format Conversion Tool for the Three NGS Platforms

Rhie A, Yang S, Lee KE, Thong CT, Park HS

  • KMID: 2166486
  • Genomics Inform.
  • 2010 Jun;8(2):97-99.
To allow for a quick conversion of the proprietary sequence data from various sequencing platforms, sequence format conversion toolkits are required that can be easily integrated into workflow systems. In...
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Java DOM Parsers to Convert KGML into SBML and BioPAX Common Exchange Formats

Lee KE, Jang MH, Rhie A, Thong CT, Yang S, Park HS

  • KMID: 2166485
  • Genomics Inform.
  • 2010 Jun;8(2):94-96.
Integrating various pathway data collections to create new biological knowledge is a challenge, for which novel computational tools play a key role. For this purpose, we developed the Java-based conversion...
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AKAPDB: A-Kinase Anchoring Proteins Database

Kim IS, Lim KJ, Han BG, Chung MG, Kim KW

  • KMID: 2166484
  • Genomics Inform.
  • 2010 Jun;8(2):90-93.
A-kinase-anchoring proteins (AKAPs) are scaffold proteins which compartmentalize protein kinase A (PKA, cAMP-dependent protein kinase) and other enzymes to specific subcellular sites. The spatiotemporal control of these enzymes by AKAPs...
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Non-Synteny Regions in the Human Genome

Lee K, Kim S

  • KMID: 2166483
  • Genomics Inform.
  • 2010 Jun;8(2):86-89.
Closely related species share large genomic segments called syntenic regions, where the genomic elements such as genes are arranged co-linearly among the species. While synteny is an important criteria in...
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Development of Optimal Breeding Pigs Using DNA Marker Information

Kim SW, Roh JG, Cho YI, Choi BH, Kim TH, Kim JJ, Kim KS

  • KMID: 2166482
  • Genomics Inform.
  • 2010 Jun;8(2):81-85.
The aim of the study was to investigate pig reference families, generated from Korean native pigs (KNP) that were crossed with Yorkshire (YS) breeds, which were used to evaluate genetic...
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No Association between Copy Number Variation of the TCRB Gene and the Risk of Autism Spectrum Disorder in the Korean Population

Yang SY, Yim SH, Hu HJ, Kim SA, Yoo HJ, Chung YJ

  • KMID: 2166481
  • Genomics Inform.
  • 2010 Jun;8(2):76-80.
Although autism spectrum disorder (ASD) has been thought to have a substantial genetic background, major contributing genes have yet to be identified or successfully replicated. Immunological dysfunction has been suggested...
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In Silico Study of Human Gap Junction Beta-2 Protein by Homology Modeling

Shehzadi A, Masood K

  • KMID: 2166480
  • Genomics Inform.
  • 2010 Jun;8(2):70-75.
Asp66his, Asp54Lys, and Asp50Asn are mutations in connexin 26 that are observed in the clinic and give rise to autosomal dominant syndromes. They are the result of point mutations in...
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A Comparative Analysis of Monofunctional Biosynthetic Peptidoglycan Transglycosylase (MBPT) from Pathogenic and Non-pathogenic Bacteria

Baker AT, Takahashi , Chandra SB

  • KMID: 2166479
  • Genomics Inform.
  • 2010 Jun;8(2):63-69.
Monofunctional biosynthetic peptidoglycan transglycosylase (MBPT) catalyzes the formation of the glycan chain in bacterial cell walls from peptidoglycan subunits: N-acetylglucosamine (NAG) and acetylmuramic acid (NAM). Bifunctional glycosyltransferases such as the...
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