- Comparative Analysis of the Three Classes of Archaeal and Bacterial Ribonucleotide Reductase from Evolutionary Perspective
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Pangare MG, Chandra SB
- KMID: 1806199
- Genomics Inform.
- 2010 Dec;8(4):170-176.
The Ribonucleotide reductases (RNR) are essential enzymes that catalyze the conversion of nucleotides to deoxynucleotides in DNA replication and repair in all living organisms. The RNRs operate by a free... -
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- Nomogram for Predicting Survival for Oral Squamous Cell Carcinoma
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Kim KY, Li S, Cha IH
- KMID: 1806205
- Genomics Inform.
- 2010 Dec;8(4):212-218.
An accurate system for predicting the survival of patients with oral squamous cell carcinoma (OSCC) will be useful for selecting appropriate therapies. A nomogram for predicting survival was constructed from... -
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- Bioinformatics Resources of the Korean Bioinformation Center (KOBIC)
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Lee B, Chu IS, Kim N, Lee J, Kim SY, Kim WK, Lee S
- KMID: 1806198
- Genomics Inform.
- 2010 Dec;8(4):165-169.
The Korean Bioinformation Center (KOBIC) is a national bioinformatics research center in Korea. We developed many bioinformatics algorithms and applications to facilitate the biological interpretation of OMICS data. Here we... -
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- Genomewide Profiling of Rapamycin Sensitivity in Saccharomyces cerevisiae on Synthetic Medium
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Chang YJ, Shin CS, Han D, Kim J, Kim K, Kwon YM, Huh WK
- KMID: 1806200
- Genomics Inform.
- 2010 Dec;8(4):177-184.
The target of rapamycin (TOR) signaling pathway is a conserved pathway that regulates eukaryotic cell growth in response to environmental cues. Chemical genomic approaches that profile rapamycin sensitivity of yeast... -
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- No Association between PIK3CA Polymorphism and Lung Cancer Risk in the Korean Population
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Sung JS, Park KH, Kim ST, Seo JH, Shin SW, Kim JS, Kim YH
- KMID: 1806202
- Genomics Inform.
- 2010 Dec;8(4):194-200.
The PIK3CA gene, oncogenic gene located on human chromosome 3q26.3, is an important regulator of cell proliferation, death, motility and invasion. To evaluate the role of PIK3CA gene in the... -
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- Single Nucleotide Polymorphism in the Promoter Region of H1 Histone Family Member N, Testis-specific (H1FNT) and Its Association Study with Male Infertility
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Yang SH, Lee J, Lee S
- KMID: 1806203
- Genomics Inform.
- 2010 Dec;8(4):201-205.
The H1 histone family, member N, testis-specific (H1FNT) is exclusively expressed in the testis, and had its possible role for sperm chromatin formation. The purpose of this study is to... -
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- Recovery of Genes Epigenetically Altered by the Histone Deacetylase Inhibitor Scriptaid and Demethylating Agent 5-Azacytidine in Human Leukemia Cells
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Park E, Jeon E, Kim IH, Park S
- KMID: 1806201
- Genomics Inform.
- 2010 Dec;8(4):185-193.
Histone deacetylation and demethylation are epigenetic mechanisms implicated in cancer. Studies regarding the role of modulation of gene expression utilizing the histone deacetylase inhibitor scriptaid and the demethylating agent 5-azacytidine... -
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- A Promoter SNP (rs1800682, -670C/T) of FAS Is Associated with Stroke in a Korean Population
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Kang SW, Chung JH, Kim DH, Yun DH, Yoo SD, Kim HS, Seo W, Yoon JS, Baik HH
- KMID: 1806204
- Genomics Inform.
- 2010 Dec;8(4):206-211.
The Fas (TNF receptor superfamily, member 6) (FAS)/FAS ligand (FASLG) interaction plays a central role in the regulation of programmed cell death. FAS and FASLG polymorphisms in promoter regions affect... -
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