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GTVseq: A Web-based Genotyping Tool for Viral Sequences

Shin JM, Park HE, Ahn YJ, Cho DH, Kim JH, Kee MK, Kim SS, Lee JS, Kim S

  • KMID: 2166323
  • Genomics Inform.
  • 2008 Mar;6(1):54-56.
Genotyping Tool for Viral SEQuences (GTVseq) provides scientists with the genotype information on the viral genome sequences including HIV-1, HIV-2, HBV, HCV, HTLV-1, HTLV-2, poliovirus, enterovirus, flavivirus, Hantavirus, and rotavirus....
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Refactoring the Code for Visualizing Protein Database Information in a 3D Viewer for Software Reusability

Chun YJ, Ham SI, Yang SD, Rhie A, Park HS

  • KMID: 2166322
  • Genomics Inform.
  • 2008 Mar;6(1):50-53.
We have released five Java Application Programming Interface (API) packages for viewing three-dimensional structures of proteins from the Protein Data Bank. To this end, the user interface of an earlier...
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Sequence Analysis and Potential Action of Eukaryotic Type Protein Kinase from Streptomyces coelicolor A3(2)

Roy DR, Chandra SB

  • KMID: 2166321
  • Genomics Inform.
  • 2008 Mar;6(1):44-49.
Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to...
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Differential Expressions of Apoptosis-related Genes in Lung Cancer Cell Lines Determine the Responsiveness to Ionizing Radiation

Lee SY, Choi MK, Lim JM, Wu HG, Kim JH, Park WY

  • KMID: 2166320
  • Genomics Inform.
  • 2008 Mar;6(1):36-43.
Radiotherapy would be the choice of treatment for human cancers, because of high cost-effectiveness. However, a certain population of patients shows a resistance to radiotherapy and recurrence. In an effort...
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Functional Prediction of Imprinted Genes in Chicken Based on a Mammalian Comparative Expression Network

Kim HY, Moon S, Kim H

  • KMID: 2166319
  • Genomics Inform.
  • 2008 Mar;6(1):32-35.
Little evidence supports the existence of imprinted genes in chicken. Imprinted genes are thought to be intimately connected with the acquisition of parental resources in mammals; thus, the predicted lack...
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Functional Haplotype Frequencies of the Interleukin-1B Promoter in the Korean Population

Lee KA

  • KMID: 2166318
  • Genomics Inform.
  • 2008 Mar;6(1):29-31.
Single nucleotide polymorphisms (SNPs) in the promoter region of the IL-1B (interleukin-1) gene have been implicated in a variety of diseases that have an inflammatory component. However, there has been...
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Chromosome 22 LD Map Comparison between Korean and Other Populations

Lee JE, Jang HY, Kim S, Yoo YK, Hwang JJ, Jun H, Lee K, Son O, Yang JM, Ahn KS, kim E, Lee HW, Song K, Kim HL, Lee SG, Yoon Y, Kimm K, Han BG, Oh B, Kim CB, Jin H, Choi KO, Kang H, Kim YJ

  • KMID: 2166317
  • Genomics Inform.
  • 2008 Mar;6(1):18-28.
Single nucleotide polymorphisms (SNPs) are the most abundant forms of human genetic variations and resources for mapping complex genetic traits and disease association studies. We have constructed a linkage disequilibrium(LD)...
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Inbreeding Coefficients in Two Isolated Mongolian Populations: GENDISCAN Study

Sung J, Lee MK, Seo JS

  • KMID: 2166316
  • Genomics Inform.
  • 2008 Mar;6(1):14-17.
GENDISCAN study (Gene Discovery for Complex traits in Asian population of Northeast area) was designed to incorporate methodologies which enhance the power to identify genetic variations underlying complex disorders. Use...
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Genome-wide Linkage Study for Plasma HDL Cholesterol Level in an Isolated Population of Mongolia

Park H, Kim JI, Cho SI, Sung J, Kim HL, Ju YS, Bayasgalan G, Lee MK, Seo JS

  • KMID: 2166315
  • Genomics Inform.
  • 2008 Mar;6(1):8-13.
High-density lipoprotein (HDL) whose primary role is to transport cholesterol from peripheral tissues to the liver, is associated with the incidence of coronary heart disease. We analyzed HDL cholesterol levels...
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Copy Number Variations in the Human Genome: Potential Source for Individual Diversity and Disease Association Studies

Kim TM, Yim SH, Chung YJ

  • KMID: 2166314
  • Genomics Inform.
  • 2008 Mar;6(1):1-7.
The widespread presence of large-scale genomic variations, termed copy number variation (CNVs), has been recently recognized in phenotypically normal individuals. Judging by the growing number of reports on CNVs, it...
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