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The AB05 NIAB Tools Workbench for Building Automatic Biopathway Maps for Agricultural Organisms

Cho MK, Yoon KO, Park HS

  • KMID: 2166289
  • Genomics Inform.
  • 2007 Dec;5(4):200-202.
For the past several years, we have built various tools for automatic construction of biopathways to help biological experts, especially in the field of agriculture. We integrated several systems for...
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Biological Object Downloader (BOD) Service for Easy Download and Management of Biological Databases

Park D, Lee J, Yoon G, Gong S, Bhak J

  • KMID: 2166287
  • Genomics Inform.
  • 2007 Dec;5(4):196-199.
BOD is an FTP service management tool on the Internet. It was developed for biological researchers in South Korea. It enables easier and faster access of bioinformation without having to...
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RGISS: Rice (Oryza sativa L. ssp. japonica) Genome Information Service System

Lee D, Seo H, Hahn JH, Kong EB, Park K

  • KMID: 2166285
  • Genomics Inform.
  • 2007 Dec;5(4):194-195.
We have constructed the Rice Genome Information Service System (RGISS), which is an information service system of the Oryza sativa L. ssp. japonica (rice) genome, using the released version of...
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FESD II: A Revised Functional Element SNP Database of Human Ethnicities

Kim HJ, Kim IH, Shin KH, Park YK, Kang H, Kim YJ

  • KMID: 2166283
  • Genomics Inform.
  • 2007 Dec;5(4):188-193.
The Functional Element SNPs Database (FESD) categorizes functional elements in human genic regions and provides a set of single nucleotide polymorphisms (SNPs) located within each area. Users may select a...
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REPEATOME: A Database for Repeat Element Comparative Analysis in Human and Chimpanzee

Woo T, Hong TH, Kim SS, Chung WH, Kang HJ, Kim CB, Seo J

  • KMID: 2166281
  • Genomics Inform.
  • 2007 Dec;5(4):179-187.
An increasing number of primate genomes are being sequenced. A direct comparison of repeat elements in human genes and their corresponding chimpanzee orthologs will not only give information on their...
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Conservation of cis-Regulatory Element Controlling Timely Translation in the 3'-UTR of Selected Mammalian Maternal Transcripts

Lee HJ, Lim Y, Chang SH, Min K, Han CT, Hwang SY

  • KMID: 2166279
  • Genomics Inform.
  • 2007 Dec;5(4):174-178.
The earliest stages of mammalian embryogenesis are governed by the activity of maternally inherited transcripts and proteins. Cytoplasmic polyadenylation of selected maternal mRNA has been reported to be a major...
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Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms

Kim Y, Kim H

  • KMID: 2166277
  • Genomics Inform.
  • 2007 Dec;5(4):168-173.
In previous nuclear genomic association studies, Random Forests (RF), one of several up-to-date machine learning methods, has been used successfully to generate evidence of association of genetic polymorphisms with diseases...
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Genetic Polymorphisms of UGT1A and their Association with Clinical Factors in Healthy Koreans

Kim JO, Shin JY, Lee MA, Chae HS, Lee CH, Roh JS, Jin SK, Kang TS, Choi JR, Kang JH

  • KMID: 2166275
  • Genomics Inform.
  • 2007 Dec;5(4):161-167.
Glucuronidation by the uridine diphosphateglucuronosyltransferase 1A enzymes (UGT1As) is a major pathway for elimination of particular drugs and endogenous substances, such as bilirubin. We examined the relation of eight single...
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Characterization of Single Nucleotide Polymorphisms in 55 Disease-Associated Genes in a Korean Population

Lee SK, Kim HG, Kang JJ, Oh W, Oh B, Kwack KB

  • KMID: 2166273
  • Genomics Inform.
  • 2007 Dec;5(4):152-160.
Most common diseases are caused by multiple genetic and environmental factors. Among the genetic factors, single nucleotide polymorphisms (SNPs) are common DNA sequence variations in individuals and can serve as...
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Calibrating Thresholds to Improve the Detection Accuracy of Putative Transcription Factor Binding Sites

Kim YJ, Ryu GM, Park C, Kim KW, Oh B, Kim YY, Gu MB

  • KMID: 2166271
  • Genomics Inform.
  • 2007 Dec;5(4):143-151.
To understand the mechanism of transcriptional regulation, it is essential to detect promoters and regulatory elements. Various kinds of methods have been introduced to improve the prediction accuracy of regulatory...
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