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Massive Identification of Cancer-Specific Nucleic Acid Ligands

Lee YJ, Lee SW

  • KMID: 1572640
  • Genomics Inform.
  • 2005 Jun;3(2):77-80.
Targeting of complex system such as human cells rather than biochemically pure molecules will be a useful approach to massively identify ligands specific for the markers associated with human disease...
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PrimateDB: Development of Primate Genome DB and Web Service

Woo T, Shin G, Kang T, Kim B, Seo J, Kim SS, Kim CB

  • KMID: 1572638
  • Genomics Inform.
  • 2005 Jun;3(2):73-76.
The comparative analysis of the human and primate genomes including the chimpanzee can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of...
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Aging and UV Irradiation Related Changes of Gene Expression in Primary Human Keratinocytes

Lee OJ, Lee SY, Park JB, Lee JY, Kim JI, Kim J

  • KMID: 1572636
  • Genomics Inform.
  • 2005 Jun;3(2):66-72.
The epidermis is a physiological barrier to protect organisms against environment. During the aging process, skin tissues undergo various changes including morphological and functional changes. The transcriptional regulation of genes...
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Comparative Genomics of T-complex protein 10 like in Humans and Chimpanzees

Kim IC, Kim DS, Kim DW, Choi SH, Choi HH, Chae SH, Park HS

  • KMID: 1572634
  • Genomics Inform.
  • 2005 Jun;3(2):61-65.
Comparing 231 genes on chimpanzee chromosome 22 with their orthologous on human chromosome 21, we have found that 15 orthologs have indels within their coding sequences. It was rather surprising...
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Classification of Peroxiredoxin Subfamilies Using Regular Expressions

Chon JK, Choi J, Kim SS, Shin W

  • KMID: 1572633
  • Genomics Inform.
  • 2005 Jun;3(2):55-60.
Peroxiredoxins (Prx's) are a superfamily of peroxidases that are ubiquitous in all super-kingdoms. Previous biochemical and structural studies have suggested that Prx's could be divided into five subfamilies (1-Cys, Typical...
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BioCovi: A Visualization Service for Comparative Genomics Analysis

Lee J, Park D, Bhak J

  • KMID: 1572632
  • Genomics Inform.
  • 2005 Jun;3(2):52-54.
Visualization of the homology information is an important method to analyze the evolutionary and functional meanings of genes. With a database containing model genomes of Homo sapiens, Mus muculus, and...
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Higher Order Knowledge Processing: Pathway Database and Ontologies

Fukuda KI

  • KMID: 1572631
  • Genomics Inform.
  • 2005 Jun;3(2):47-51.
Molecular mechanisms of biological processes are typically represented as "pathways" that have a graph-analogical network structure. However, due to the diversity of topics that pathways cover, their constituent biological entities...
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