- Comparative Genomics Study of Interferon-alpha Receptor-1 in Humans and Chimpanzees
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Kim IC, Chi SW, Kim DW, Choi SH, Chae SH, Park HS
- KMID: 2284673
- Genomics Inform.
- 2005 Dec;3(4):142-148.
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human... -
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- Specificity of Intracellular Trans-Splicing Reaction by hTERT-Targeting Group I Intron
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Jung HS, Kwon BS, Lee SW
- KMID: 2284678
- Genomics Inform.
- 2005 Dec;3(4):172-174.
Recent anti-cancer approaches have been based to target tumor-specifically associated and/or causative molecules such as RNAs or proteins. As this specifically targeted anti-cancer modulator, we have previously described a novel... -
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- X-linked Gene Expression Profiles by RNAi-Mediated BRCA1 Knockdown in MCF7 Cells
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Song MA, Park JH, Ahn HJ, Ko JJ, Lee S
- KMID: 2284675
- Genomics Inform.
- 2005 Dec;3(4):154-158.
Germ-line mutations of the BRCA1 gene confer an increased risk for breast and ovarian cancers. BRCA1 in female cells is directly related with the maintenance of the inactive X chromosome... -
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- Estimating the Genetic Epidemiology Parameters of Selected Cancers in Korea Population: The Korean Twin Study
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Sung J
- KMID: 2284676
- Genomics Inform.
- 2005 Dec;3(4):159-165.
The Korean Twin Register (n=154,783 pairs) was reported in 2002 as the first nationwide twin study in Korea and the largest study in Asia. The Twin Register has the information... -
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- Genomic Features of Retroelements and Implications for Human Disease
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Kim HS
- KMID: 2284672
- Genomics Inform.
- 2005 Dec;3(4):133-141.
Most of the endogenous retroviral genes integrated into the primate genome after the split of New World monkeys in the Oligocene era, approximately 33 million years ago. Because they can... -
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- Genetic Variants of IL-13 and IL-4 in the Korean Population: Polymorphisms, Haplotypes and Linkage Disequilibrium
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Ryu HJ, Jung HY, Park JS, Kim JW, Kim HT, Park CS, Han BG, Koh I, Park C, Kimm K, Oh B, Lee JK
- KMID: 2284674
- Genomics Inform.
- 2005 Dec;3(4):149-153.
Asthma is an inflammatory airways disease characterized by bronchial hyperresponsiveness and airways obstruction, which results from a complex interaction of genetic and environmental factors. Interleukin (IL)-13 and IL-4 are important... -
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- A Cotwin Control Study of Smoking and Risk Factors of Metabolic Syndrome
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Sung J, Cho SI, Choi JS, Song YM, Lee K, Choi EY, Ha M, Kim Y, Shin EK
- KMID: 2284677
- Genomics Inform.
- 2005 Dec;3(4):166-171.
BACKGROUND: Smoking effects are relatively well-documented, especially on cancers and cardiovascular diseases. However, the direction and magnitude of association between smoking and obesity remain unclear. Conflicting results so far are... -
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