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Specificity of Intracellular Trans-Splicing Reaction by hTERT-Targeting Group I Intron

Jung HS, Kwon BS, Lee SW

  • KMID: 2284678
  • Genomics Inform.
  • 2005 Dec;3(4):172-174.
Recent anti-cancer approaches have been based to target tumor-specifically associated and/or causative molecules such as RNAs or proteins. As this specifically targeted anti-cancer modulator, we have previously described a novel...
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A Cotwin Control Study of Smoking and Risk Factors of Metabolic Syndrome

Sung J, Cho SI, Choi JS, Song YM, Lee K, Choi EY, Ha M, Kim Y, Shin EK

  • KMID: 2284677
  • Genomics Inform.
  • 2005 Dec;3(4):166-171.
BACKGROUND: Smoking effects are relatively well-documented, especially on cancers and cardiovascular diseases. However, the direction and magnitude of association between smoking and obesity remain unclear. Conflicting results so far are...
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Estimating the Genetic Epidemiology Parameters of Selected Cancers in Korea Population: The Korean Twin Study

Sung J

  • KMID: 2284676
  • Genomics Inform.
  • 2005 Dec;3(4):159-165.
The Korean Twin Register (n=154,783 pairs) was reported in 2002 as the first nationwide twin study in Korea and the largest study in Asia. The Twin Register has the information...
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X-linked Gene Expression Profiles by RNAi-Mediated BRCA1 Knockdown in MCF7 Cells

Song MA, Park JH, Ahn HJ, Ko JJ, Lee S

  • KMID: 2284675
  • Genomics Inform.
  • 2005 Dec;3(4):154-158.
Germ-line mutations of the BRCA1 gene confer an increased risk for breast and ovarian cancers. BRCA1 in female cells is directly related with the maintenance of the inactive X chromosome...
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Genetic Variants of IL-13 and IL-4 in the Korean Population: Polymorphisms, Haplotypes and Linkage Disequilibrium

Ryu HJ, Jung HY, Park JS, Kim JW, Kim HT, Park CS, Han BG, Koh I, Park C, Kimm K, Oh B, Lee JK

  • KMID: 2284674
  • Genomics Inform.
  • 2005 Dec;3(4):149-153.
Asthma is an inflammatory airways disease characterized by bronchial hyperresponsiveness and airways obstruction, which results from a complex interaction of genetic and environmental factors. Interleukin (IL)-13 and IL-4 are important...
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Comparative Genomics Study of Interferon-alpha Receptor-1 in Humans and Chimpanzees

Kim IC, Chi SW, Kim DW, Choi SH, Chae SH, Park HS

  • KMID: 2284673
  • Genomics Inform.
  • 2005 Dec;3(4):142-148.
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human...
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Genomic Features of Retroelements and Implications for Human Disease

Kim HS

  • KMID: 2284672
  • Genomics Inform.
  • 2005 Dec;3(4):133-141.
Most of the endogenous retroviral genes integrated into the primate genome after the split of New World monkeys in the Oligocene era, approximately 33 million years ago. Because they can...
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