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Heterologous Regulation of BCG hsp65 Promoter by M. leprae 18 kDa Transcription Repression Responsive Element

Kim HB, You JC

  • KMID: 2053075
  • Genomics Inform.
  • 2003 Dec;1(2):113-118.
Among a number of antigens characterized in M. leprae, an etiological agent of Leprosy, the 18 kDa antigen, is unique to M. leprae. We have previously determined a sequence specific...
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Combined Genome Mapping of RFLP-AFLP-SSR in Pepper

Lee JM, Kim BD

  • KMID: 2053074
  • Genomics Inform.
  • 2003 Dec;1(2):108-112.
We have constructed a molecular linkage map of pepper (Capsicum spp.) in an interspecific F2 population of 107 plants with 320 RFLP, 136 AFLP, and 46 SSR markers. The resulting...
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Construction of Deletion Map of 16q by LOH Analysis from HCC Patients and Physical Map on 16q 23.3 - 24.1 Region

Chung J, Choi NY, Shim MS, Choi DW, Kang HS, Kim CM, Kim UJ, Park SH, Kim H, Lee BJ

  • KMID: 2053073
  • Genomics Inform.
  • 2003 Dec;1(2):101-107.
Loss of heterozygosity (LOH) has been used to detect deleted regions of a specific chromosome in cancer cells. LOH on chromosome 16q has been reported to occur frequently in progressed...
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Rank-Based Nonlinear Normalization of Oligonucleotide Arrays

Park PJ, Kohane IS, Kim JH

  • KMID: 2053072
  • Genomics Inform.
  • 2003 Dec;1(2):94-100.
MOTIVATION: Many have observed a nonlinear relationship between the signal intensity and the transcript abundance in microarray data. The first step in analyzing the data is to normalize it properly,...
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Poor Correlation Between the New Statistical and the Old Empirical Algorithms for DNA Microarray Analysis

Kim JH, Kuo WP, Kong SW, Machado LO, Kohane IS

  • KMID: 2053071
  • Genomics Inform.
  • 2003 Dec;1(2):87-93.
DNA microarray is currently the most prominent tool for investigating large-scale gene expression data. Different algorithms for measuring gene expression levels from scanned images of microarray experiments may significantly impact...
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Classification of Human Papillomavirus (HPV) Risk Type via Text Mining

Park SB, Hwang S, Zhang BT

  • KMID: 2053070
  • Genomics Inform.
  • 2003 Dec;1(2):80-86.
Human Papillomavirus (HPV) infection is known as the main factor for cervical cancer which is a leading cause of cancer deaths in women worldwide. Because there are more than 100...
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Interpretation of Association Networks among Protein Sequence Motifs

Kam HJ, Lee J, Lee D, Lee KH

  • KMID: 2053069
  • Genomics Inform.
  • 2003 Dec;1(2):75-79.
Every protein can be characterized by either a distinct motif or a combination of motifs. Nevertheless, little is known about the relationships among (more than two) the motifs. Some of...
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Data Mining for High Dimensional Data in Drug Discovery and Development

Lee KR, Park DC, Lin X, Eslava S

  • KMID: 2053068
  • Genomics Inform.
  • 2003 Dec;1(2):65-74.
Data mining differs primarily from traditional data analysis on an important dimension, namely the scale of the data. That is the reason why not only statistical but also computer science...
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