- Human Population Admixture in Asia
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Xu S
- KMID: 1806242
- Genomics Inform.
- 2012 Sep;10(3):133-144.
- doi: 10.5808/GI.2012.10.3.133
Genetic admixture in human, the result of inter-marriage among people from different well-differentiated populations, has been extensively studied in the New World, where European colonization brought contact between peoples of... -
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- Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
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Krishnan J, Choi S
- KMID: 1806244
- Genomics Inform.
- 2012 Sep;10(3):153-166.
- doi: 10.5808/GI.2012.10.3.153
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of... -
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- Effect of Combining Multiple CNV Defining Algorithms on the Reliability of CNV Calls from SNP Genotyping Data
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Kim SY, Kim JH, Chung YJ
- KMID: 1806248
- Genomics Inform.
- 2012 Sep;10(3):194-199.
- doi: 10.5808/GI.2012.10.3.194
In addition to single-nucleotide polymorphisms (SNP), copy number variation (CNV) is a major component of human genetic diversity. Among many whole-genome analysis platforms, SNP arrays have been commonly used for... -
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- Discovery and Evaluation of Polymorphisms in the AKT2 and AKT3 Promoter Regions for Risk of Korean Lung Cancer
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Sung JS, Park KH, Kim ST, Kim YH
- KMID: 1806245
- Genomics Inform.
- 2012 Sep;10(3):167-174.
- doi: 10.5808/GI.2012.10.3.167
AKT is a signal transduction protein that plays a central role in the tumorigenesis. There are 3 mammalian isoforms of this serine/threonine protein kinase-AKT1, AKT2, and AKT3-showing a broad tissue... -
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- Characterization of Chromatin Structure-associated Histone Modifications in Breast Cancer Cells
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Hong CP, Choe MK, Roh TY
- KMID: 1806243
- Genomics Inform.
- 2012 Sep;10(3):145-152.
- doi: 10.5808/GI.2012.10.3.145
Chromatin structure and dynamics that are influenced by epigenetic marks, such as histone modification and DNA methylation, play a crucial role in modulating gene transcription. To understand the relationship between... -
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- Comparison of SNP Variation and Distribution in Indigenous Ethiopian and Korean Cattle (Hanwoo) Populations
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Edea Z, Dadi H, Kim SW, Dessie T, Kim KS
- KMID: 1806249
- Genomics Inform.
- 2012 Sep;10(3):200-205.
- doi: 10.5808/GI.2012.10.3.200
Although a large number of single nucleotide polymorphisms (SNPs) have been identified from the bovine genome-sequencing project, few of these have been validated at large in Bos indicus breeds. We... -
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- Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans
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Yoo JY, Kim SY, Hwang JA, Hong SH, Shin A, Choi IJ, Lee YS
- KMID: 1806247
- Genomics Inform.
- 2012 Sep;10(3):184-193.
- doi: 10.5808/GI.2012.10.3.184
Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types.... -
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- Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II)
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Jo J, Nam CM, Sull JW, Yun JE, Kim SY, Lee SJ, Kim YN, Park EJ, Kimm H, Jee SH
- KMID: 1806246
- Genomics Inform.
- 2012 Sep;10(3):175-183.
- doi: 10.5808/GI.2012.10.3.175
Colorectal cancer (CRC) is among the leading causes of cancer deaths and can be caused by environmental factors as well as genetic factors. Therefore, we developed a prediction model of... -
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- DNA Barcoding of Fish, Insects, and Shellfish in Korea
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Kim DW, Yoo WG, Park HC, Yoo HS, Kang DW, Jin SD, Min HK, Paek WK, Lim J
- KMID: 1806250
- Genomics Inform.
- 2012 Sep;10(3):206-211.
- doi: 10.5808/GI.2012.10.3.206
DNA barcoding has been widely used in species identification and biodiversity research. A short fragment of the mitochondrial cytochrome c oxidase subunit I (COI) sequence serves as a DNA bio-barcode.... -
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