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COCAW: A Genome-wide Pattern Search System for Designing Microbial Probes

Ryu S, Park K, Lee D, Kim CM

  • KMID: 1469580
  • Genomics Inform.
  • 2009 Sep;7(3):178-180.
A few bioinformatics tools have been used to find out conserved regions as probes. We have developed a system based on a heuristic method with web interfaces to find out...
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The Effect of Increasing Control-to-case Ratio on Statistical Power in a Simulated Case-control SNP Association Study

Kang M, Choi S, Koh I

  • KMID: 1469573
  • Genomics Inform.
  • 2009 Sep;7(3):148-151.
Generally, larger sample size leads to a greater statistical power to detect a significant difference. We may increase the sample size for both case and control in order to obtain...
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WinBioDBs: A Windows-based Integrated Program for Manipulating Major Biological Databases

Nam H, Lee JH, Park K

  • KMID: 1469579
  • Genomics Inform.
  • 2009 Sep;7(3):175-177.
We have developed WinBioDBs with Windows interfaces, which include importing modules and searching interfaces for 10 major public databases such as GenBank, PIR, SwissProt, Pathway, EPD, ENZYME, REBASE, Prosite, Blocks,...
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A Computer-aided Design Tool with Semiautomatic Image-Processing Features for Visualizing Biological Pathways

Ham SI, Yang SD, Thong CT, Park HS

  • KMID: 1469577
  • Genomics Inform.
  • 2009 Sep;7(3):168-170.
The explosion in biological data resulting from highthroughput experiments requires new software tools to manipulate and display pathways in a way that can integrate disparate sources of information. A visual...
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J2.5dPathway: A 2.5D Visualization Tool to Display Selected Nodes in Biological Pathways, in Parallel Planes

Ham SI, Song EH, Yang SD, Thong CT, Rhie A, Galbadrakh B, Lee KE, Park HS, Lee SH

  • KMID: 1469578
  • Genomics Inform.
  • 2009 Sep;7(3):171-174.
The characteristics of metabolic pathways make them particularly amenable to layered graph drawing methods. This paper presents a visual Java-based tool for drawing and annotating biological pathways in twoand- a-half...
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A New Approach to Find Orthologous Proteins Using Sequence and Protein-Protein Interaction Similarity

Kim MK, Seol YJ, Park HS, Jang SH, Shin HC, Cho KH

  • KMID: 1469572
  • Genomics Inform.
  • 2009 Sep;7(3):141-147.
Developed proteome-scale ortholog and paralog prediction methods are mainly based on sequence similarity. However, it is known that even the closest BLAST hit often does not mean the closest neighbor....
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Detection of hydin Gene Duplication in Personal Genome Sequence Data

Kim JI, Ju YS, Kim S, Hong D, Seo JS

  • KMID: 1469575
  • Genomics Inform.
  • 2009 Sep;7(3):159-162.
Human personal genome sequencing can be done with high efficiency by aligning a huge number of short reads derived from various next generation sequencing (NGS) technologies to the reference genome...
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The Korean Pharmacogenomic Database at NIFDS: 2008 Update

Kang TS, Woo SW, Park HJ, Han SY, Park MH, Chung MW

  • KMID: 1469576
  • Genomics Inform.
  • 2009 Sep;7(3):163-167.
Since its first release in 2007, the National Institute of Food and Drug Safety Evaluation (NIFDS) has provided pharmacogenomic and comparative information specific to Koreans to allow regulatory reviewers and...
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Localization of Quantitative Trait Loci for Bone Mineral Density on Chromosome 13 in the Mongolian Population

Seo SH, Lim HJ, Ahn S, Lee J, Kim JI

  • KMID: 1469574
  • Genomics Inform.
  • 2009 Sep;7(3):152-158.
Although the genetic basis for bone mineral density (BMD) has been studied by many groups so far, genes responsible for this complex trait has not been completely revealed. In order...
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