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p53 codon 72 polymorphism and risk of cervical carcinoma in Korean women

Baek WK, Cho JW, Suh SI, Suh MH, Shin DH, Cho CH, Lee TS, Cha SD

A common polymorphism of the wild type p53 is known at codon 72 of exon 4, with 2 alleles encoding either arginine (CGC, p53Arg) or proline (CCC, p53Pro). A recent...
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Detecting p53 gene mutation of breast cancer and defining differences between silver staining PCR-SSCP and immunohistochemical staining

Ryu JW, Lee MC, Jang WC

This study detects and defines the patterns of p53 gene mutations in breast cancers. We analyse p53 gene mutations through comparing the results of single-strand-conformation-polymorphism (SSCP) and immunohistochemistry (IHC), and...
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