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Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice

Krishnan J, Chen J, Shin KJ, Hwang JI, Han SU, Lee G, Choi S

Exposure to light can induce photoreceptor cell death and exacerbate retinal degeneration. In this study, mice with genetic knockout of several genes, including rhodopsin kinase (Rhok-/-), arrestin (Sag-/-), transducin (Gnat1-/-),...
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Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY

  • KMID: 1093610
  • Exp Mol Med.
  • 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
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