- Progressive De Novo DNA Methylation at the Pa Promotor of the Abl Genein the Bcr-Abl Locus during the Course of Chronic Myelogenous Leukemia
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Yang SE, Chi HS
- KMID: 2089552
- Korean J Clin Pathol.
- 1998 Sep;18(3):480-486.
BACKGROUND: In most cases of chronic myelogenous leukemia (CML), one of the two abl promotors (Pa) is nested within the bcr-abl hybrid gene and should be able to transcribe the... -
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- Detection of Major bcr-abl mRNA Using One Step RT-PCR
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Kang CS, Lee EJ, Yoo JB, Kim DH, Kim DE, Yang IH, Oh EJ, Kim Y, Kim WI
- KMID: 1907542
- J Clin Pathol Qual Control.
- 1997 Dec;19(2):273-279.
BACKGROUND: Chronic myelogenous leukemia (CML) is characterized by fusion of bcr and abl genes from which major bcr-abl mRNA is generated. To detect major bcr-abl mRNA, reverse transcription-polymerase chain reaction... -
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- Analysis of Breakpoints of bcr-abl Fusion Gene Using RT-PCR
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Shin S, Park SS, Cho HI, Hur M, Lee YJ
- KMID: 2031000
- Korean J Clin Pathol.
- 1999 Aug;19(4):369-374.
BACKGROUND: Three types of chimeric mRNA can be expressed as a result of fusion of abl gene on chromosome 9 and bcr gene on chromosome 22. These are b3a2, b2a2,... -
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- Diagnostic Usefulness of the Janus Kinase 2 Mutation in non BCR/ABL Myeloproliferative Disorders
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Bang SM, Ahn JY, Park J, Yoo SJ, Park SH, Nam EM, Park PW, Seo YH, Cho EK, Shin DB, Lee JH
- KMID: 759854
- Korean J Intern Med.
- 2006 Dec;21(4):219-224.
- doi: 10.3904/kjim.2006.21.4.219
BACKGROUND: We investigated the Janus kinase 2 (JAK2) mutation and its diagnostic value in patients suffering with non BCR/ABL myeloproliferative diseases (nMPD) or other reactive conditions. METHODS: We... -
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