- Immediate early genes and preproenkephalin gene expression in the rat nucleus caudalis after trigeminal stimulation
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Cho HJ, Lee HS, Joo K
- KMID: 1686599
- Korean J Anat.
- 1993 Dec;26(4):352-360.
No abstract available. -
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- A study on the expression of immediate-early genes by light stimuli in the rat suprachiasmatic nucleus using differential display
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Park HT, Kim WI, Kang EK, Park JK, Bae KW
- KMID: 2040090
- Korean J Anat.
- 1999 Aug;32(4):451-457.
The hypothalamic suprachiasmatic nucleus (SCN) of the mammal is the circadian pacemaker responsible for generation of circadian rhythms. Several immediate-early genes are expressed in the SCN by light stimuli which... -
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- The expression of the immediate early genes, c-fos, krox-24 and the late response gene, BKNF induced by antiepileptic drugs
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Suh SC, Park YC, Kim SK
- KMID: 2066085
- J Korean Neurol Assoc.
- 1997 Jun;15(3):542-554.
The expression of the c-fos and krox-24 (immediate early genes: IEGs) and the BDNF (late response gene) were investigated by convulsants such as kainate (KA, 200 micrometer), N-methyl-D-aspartate (NMDA, 10... -
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- Expression of Immediate Early Genes Messenger RNAs in Focally Ischemic Rat Brain Following Delayed Postischemic Hyperthermia
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Kim Y, Ginsberg M
- KMID: 2188163
- J Korean Neurosurg Soc.
- 1998 May;27(5):563-569.
Previous studies have indicated that hyperthermic modulation in the delayed postischemic period, even when occurring days after an ischemic insult, may augment ischemic injury. In order to evaluate the molecular... -
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- The Induction of Immediate Early Genes and Phosphorylation of p42, p44 MAPK and Elk-1 by Kainic Acid in Developing Rat Hippocampus
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Jung HY, Kim SJ, Kim JH, Chung SJ, Park JB, Kim YS, Cho SC
- KMID: 2340349
- J Korean Neuropsychiatr Assoc.
- 1999 Jul;38(4):894-903.
OBJECTIVES: In order to investigate the maturational process of intracellular signal transduction system in rat brain, we studied the induction of the immediate early genes(IEGs)c-fos, junB, and TIS1 in... -
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- Neurobiology of Depression
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Kim YH, Lee SK, Rhee CG, Kim JI
- KMID: 2334586
- J Korean Soc Biol Psychiatry.
- 1999 Jul;6(1):3-11.
At the beginning, researches on the biology of depression or affective illness have focused mainly on the receptor functions and neuroendocrine activities. And the studies of the past years did... -
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- Propofol-induced Immediate Early Gene Expression in Human Neuroblastoma Cell Lines
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Kim DI, Kim JR, Kim SY
- KMID: 2244022
- Korean J Anesthesiol.
- 2008 Feb;54(2):189-196.
- doi: 10.4097/kjae.2008.54.2.189
BACKGROUND: General anesthetics were known to induce expression of immediate early genes (IEGs), including c-fos and c-jun. However, mechanisms of IEG induction by general anesthetics were not fully understood. METHODS: IEG... -
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- Expression of Activating Transcription Factor 3 in Ischemic Penumbra Region Following Focal Cerebral Ischemia
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Song DY, OH KM, Lee JH, Woo RS, Lee YJ, Han JT, Baik TK
- KMID: 2092940
- Korean J Anat.
- 2008 Sep;41(3):173-183.
It has been demonstrated that some of immediate early genes (IEGs) such as c-Jun or fos are induced immediately following neuronal injury and they play an important role in determining... -
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- c-Jun Protein Expression and Seizure-induced Neuronal Damage on Hippocampal Explant Cultures of Rat in Different Maturation Stage
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Chae SA, Lee KI, Choi ES
- KMID: 2007389
- J Korean Child Neurol Soc.
- 2003 Nov;11(2):225-233.
PURPOSE: Immaure brain is more resistant to seizure-induced neuronal damage than the adult brain in animal study. Immediate early genes such as c-jun play a critical role in neuronal damage.... -
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- The effect of aflatoxin B1 on the expression of early response genes and transforming growth factor-alpha in CCl4 induced rat liver injury
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Hong SW, Park C
- KMID: 699946
- Yonsei Med J.
- 1997 Jun;38(3):167-177.
- doi: 10.3349/ymj.1997.38.3.167
Aflatoxin B1 (AFB1), a fungal toxin produced by Aspergillus flavus, is known to be a possible hepatocarcinogen. But the molecular biologic changes which may occur following exposure to... -
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- Memantine Attenuates Salicylate-induced Tinnitus Possibly by Reducing NR2B Expression in Auditory Cortex of Rat
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Jang CH, Lee S, Park IY, Song A, Moon C, Cho GW
- KMID: 2458547
- Exp Neurobiol.
- 2019 Aug;28(4):495-503.
- doi: 10.5607/en.2019.28.4.495
Memantine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) receptor, suppresses the release of excessive levels of glutamate that may induce neuronal excitation. Here we investigated the effects of memantine on... -
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- Suppression of the ERK–SRF axis facilitates somatic cell reprogramming
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Huh S, Song HR, Jeong GR, Jang H, Seo NH, Lee JH, Yi JY, Lee B, Choi HW, Do JT, Kim JS, Lee SH, Jung JW, Lee T, Shim J, Han MK, Lee TH
- KMID: 2440030
- Exp Mol Med.
- 2018 Feb;50(2):e448.
- doi: 10.1038/emm.2017.279
The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination... -
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- Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants
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Kim DK, Huh JE, Lee SH, Hong KP, Park JE, Seo JD, Lee WR
- KMID: 646015
- J Korean Med Sci.
- 1999 Oct;14(5):487-496.
- doi: 10.3346/jkms.1999.14.5.487
It has been proposed that the local renin-angiotensin system is activated in the adventitia after vascular injury. However, the physiological role of Angiotensin II (Ang II) in the adventitia has... -
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- Activation of cAMP-Response Element Binding Protein in the Brain Stem Nuclei during Vestibular Compensation in Unilateral Labyrinthectomizied Rats
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Woon SD, Lee JH, Kim JH, Kim MS, Park BR
- KMID: 1923192
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Dec;44(12):1242-1252.
BACKGROUND AND OBJECTIVES: The p-CREB (phospholyated form of cAMP/calcium response element binding protein) was known to be one of transcription factors for immediate early genes in the brain stem nuclei.... -
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- Expression of Immediate-Early Gene Proteins by Transient Occlusion of Anterior Inferior Cerebellar Artery in Vestibular Nuclei of Sprague-Dawley Rats
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Lee HS, Han HS, Lee HS, Park SW, Park HY, Chang H, Kim YS, Cho KH, Kim MS, Choi MA, Park BR
- KMID: 2343085
- J Korean Neurol Assoc.
- 2004 Aug;22(4):360-367.
BACKGROUND: Anterior cerebellar artery (AICA) occlusion results in vestibular dysfunctions because the AICA supplies the vestibular nuclei (VN) in the brain stem as well as the peripheral vestibular organs in... -
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- Immunohistochemical Study for Expression of cFos-like Protein Induced by Acute Hypotension in Rat Brain
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Wi DH, Park JH
- KMID: 2331236
- J Korean Soc Emerg Med.
- 1998 Dec;9(4):505-514.
BACKGROUND: It has been well known that cFos protein, one of the immediate-early gene proteins, was a cellular marker to characterize physiological or anatomical property of neural networks in mammalian... -
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