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The Clinical Significance of Mutation in the p53, DCC and nm23 Genes in Patients with Gastric Carcinoma

Hwang SH, Oh SH, Choi YK

  • KMID: 1599423
  • Korean J Gastroenterol.
  • 2001 Nov;38(5):325-335.
BACKGROUND/AIMS: Multiple gene abnormalities are observed in gastric carcinogenesis. We analyzed the mutation of p53, DCC and nm23 genes in gastric carcinoma and evaluated their clinical significance. METHODS: Mutations of p53,...
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DCC Gene and Protein Expression in Colorectal Cancer

Kim JI, Jeong HJ, Yang YI, Paik KH, Yoon HK, Hong KH, Choi KH

  • KMID: 1626389
  • J Korean Soc Coloproctol.
  • 2003 Feb;19(1):26-37.
PURPOSE: The germline, or somatic, inactivation of tumor suppressor genes, through point mutation, or deletion, plays an important role in carcinogenesis. Several gene alterations, such as adenomatous polyposis coli (APC),...
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Role of DCC(Deleted in Colorectal Cancer) Gene in Oral Squamous Cell Carcinoma

Ko SK, Han SJ, Kim KW

  • KMID: 2005383
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Oct;34(5):518-524.
Chromosome 18q alteration plays a key role in colorectal tumorigenesis, and loss of heterozygosity at 18q is associated with a poor prognosis in colon cancer. DCC(Deleted in Colorectal Cancer) is...
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The Expression of DCC Protein in Colorectal Carcinomas

Kim JW, Ahn DH, Chung JS, Lee KP

  • KMID: 2101286
  • J Korean Soc Coloproctol.
  • 1997 Sep;13(3):317-324.
Colorectal cancer is one of the malignant tumours of which molecular genetic alterations have been much unveiled among the human cancers. In the multi-stepwise process to the carcinogenesis, it has...
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