- Adenovirus-mediated p53 tumor suppressor gene therapy against subcutaneous HuH7 hepatoma cell line nodule of nude mice
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Choi JY, Park YM, Byun BH, Kim BS, Hong EG, Shin DY, Seong YR, Im DS
- KMID: 646305
- J Korean Med Sci.
- 1999 Jun;14(3):271-276.
- doi: 10.3346/jkms.1999.14.3.271
Mutations of the tumor-suppressor gene p53 have been found in 30-50% cases of hepatocellular carcinoma (HCC). In this study, E1-negative adenoviral vector encoding wild-type p53 under the control of the... -
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- Low-dose radiation response of the p21(WAF1/CIP1) gene promoter transduced by adeno-associated virus vector
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Nenoi M, Daino K, Ichimura S, Takahash S, Akuta T
- KMID: 1098090
- Exp Mol Med.
- 2006 Oct;38(5):553-564.
In cancer gene therapy, restriction of antitumor transgene expression in a radiation field by use of ionizing radiation-inducible promoters is one of the promising approaches for tumor-specific gene delivery. Although... -
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- Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
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Chen B, Qin J, Wang H, Magdalou J, Chen L
- KMID: 964663
- Exp Mol Med.
- 2010 Oct;42(10):684-695.
- doi: 10.3858/emm.2010.42.10.067
The study investigated the effects of adenovirus-mediated gene transfection of basic fibroblast growth factor (bFGF), bFGF combined with interleukin-1 receptor antagonist protein (IL-Ra) and/or insulin-like growth factor-1 (IGF-1) both in... -
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- Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy
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Kim EJ, Yoo JY, Choi YH, Ahn KJ, Lee JD, Yun CO, Yun M
- KMID: 2158200
- Yonsei Med J.
- 2008 Oct;49(5):811-818.
- doi: 10.3349/ymj.2008.49.5.811
PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression... -
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- Tissue engineering applications in the genitourinary tract system
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Yoo JJ, Atala A
- KMID: 1114567
- Yonsei Med J.
- 2000 Dec;41(6):789-802.
- doi: 10.3349/ymj.2000.41.6.789
The concept of cell transplantation using tissue engineering techniques has provided numerous possibilities in the area of urologic tissue reconstruction. Tissue engineering applications in the genitourinary tract system have been... -
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