- miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1
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Arora H, Qureshi R, Jin S, Park AK, Park WY
- KMID: 1009969
- Exp Mol Med.
- 2011 May;43(5):298-304.
- doi: 10.3858/emm.2011.43.5.031
The activation of nuclear factor-kappa B1 (NFkappaB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency of IR in lung cancer, we screened for... -
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- Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells
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Chin C, Bae JH, Kim MJ, Hwang JY, Kim SJ, Yoon MS, Lee MK, Kim DW, Chung BS, Kang CD, Kim SH
- KMID: 1116206
- Exp Mol Med.
- 2005 Dec;37(6):608-618.
Here we determined which radiation-responsive genes were altered in radioresistant CEM/IR and FM3A/IR variants, which showed higher resistance to irradiation than parental human leukemia CEM and mouse mammary carcinoma FM3A... -
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- Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation
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Kim JY, Son YO, Park SW, Bae JH, Chung JS, Kim HH, Chung BS, Kim SH, Kang CD
- KMID: 1098081
- Exp Mol Med.
- 2006 Oct;38(5):474-484.
In this study, we have investigated if current cancer therapeutic modalities including hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in human cancer cell lines. The expressions... -
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