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Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease: implications for neuronal loss in Gaucher disease

Kim EY, Hong YB, Go SH, Lee B, Jung SC

  • KMID: 1110118
  • Exp Mol Med.
  • 2006 Aug;38(4):348-356.
Gaucher disease is a glycosphingolipid storage disease caused by deficiency of glucocerebrosidase, resulting in the accumulation of glucosylceramide in lysosomes. The neuronopathic forms of this disease are associated with neuronal...
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