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Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm

Cha JH, Jang JS

Background/Aims: The relationship between the serum pepsinogen (sPG) level and changes in gastric mucosa has been well studied. Here, we evaluated the usefulness of sPG (I, II, I/II ratio) and...
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Astaxanthin Inhibits Helicobacter pylori-induced Inflammatory and Oncogenic Responses in Gastric Mucosal Tissues of Mice

Han H, Lim JW, Kim H

Helicobacter pylori is recognized as a risk factor for gastric carcinogenesis. The chronic exposure of gastric epithelium to H. pylori induces a prolonged inflammatory state that may progress to gastric...
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Ileal Heterotopic Gastric Mucosa with Small Bowel Obstruction Mimicking Inflammatory Bowel Disease: A Case Study

Cho JY, Woo JY, Hong HS, Yang I, Moon JH, Hwang JY, Kim HM, Kim HY, Kim HJ, Kim JW

Gastric heterotopia rarely occurs in the ileum without a Meckel's diverticulum. We report a case of a 53-year-old man who presented with recurrent abdominal pain. The initial computed tomography (CT)...
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Endoscopic Treatment of Jejunal Heterotopic Gastric Mucosa that Caused Recurrent Intussusception

Ahn KR, Koo JS, Kim HI, Kim JH, Lee JH, Kim SY, Jung SW, Lee SW

Heterotopic gastric mucosa (HGM) is a rare anomaly in the small bowel and may be the cause of intussusception when it gets a lead point in the jejunum. All cases...
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Comparison of Gastric Microbiota Between Gastric Juice and Mucosa by Next Generation Sequencing Method

Sung J, Kim N, Kim J, Jo HJ, Park JH, Nam RH, Seok YJ, Kim YR, Lee DH, Jung HC

BACKGROUND: Not much is known about the role of gastric microbiota except for Helicobacter pylori in human health and disease. In this study, we aimed to detect human gastric microbiota...
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Does Helicobacter pylori Exacerbate Gastric Mucosal Injury in Users of Nonsteroidal Anti-Inflammatory Drugs? A Multicenter, Retrospective, Case-Control Study

Kono Y, Okada H, Takenaka R, Miura K, Kanzaki H, Hori K, Kita M, Tsuzuki T, Kawano S, Kawahara Y, Yamamoto K

BACKGROUND/AIMS: The interaction between nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori remains controversial. We retrospectively investigated whether H. pylori infection exacerbates severe gastric mucosal injury among chronic NSAID users. METHODS: From...
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The Efficacy of an Endoscopic Grasp-and-Traction Device for Gastric Endoscopic Submucosal Dissection: An Ex Vivo Comparative Study (with Video)

Scholvinck DW, Goto O, Bergman JJ, Yahagi N, Weusten BL

BACKGROUND/AIMS: To investigate whether the EndoLifter (Olympus), a counter-traction device facilitating submucosal dissection, can accelerate endoscopic submucosal dissection (ESD). METHODS: Two endoscopists (novice/expert in ESD) performed 64 ESDs (artificial 3-cm lesions)...
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A Case of PICOLIGHT Powder Induced Thermal Injury of the Gastric Mucosa

Lee DS, Kim HS, Lee SH, Jeon JH, Lee YK

There are many reports about causes of corrosive agents such as acids and alkaline and occasionally hot food in either liquid or solid forms as causes of upper gastrointestinal mucosal...
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Protective effect of halophyte Salsola komarovi Iljin against gastric ulcer Induced by alcohol treatment in rats

Hong S, Lee HA, Lee YS, Kim DW, Oh GW, Woo J, Cho Y, Jeong JH, Kim O

Salsola komarovi Iljin is a halophyte and herbaceous annual native to the sand dunes and beaches of Japan, northern China, Sakhalin, and Korea. The plants have been known as an...
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Single-incision intragastric resection for upper and mid gastric submucosal tumors: a case-series study

Choi CI, Lee SH, Hwang SH, Kim DH, Jeon TY, Kim DH, Kim GH, Park DY

PURPOSE: Laparoscopic gastric wedge resection is a standard treatment for removing gastric submucosal tumors (SMTs). So far, however, there have been few reports of single-incision laparoscopic intragastric wedge resection. Our...
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The Feasibility of Using Simulated Targets in the Stomachs of Live Pigs for Full Endoscopic Submucosal Dissection Training

Wang HY, Shih SC, Hung CY, Liu CY, Shieh TY, Chen MJ

BACKGROUND/AIMS: In endoscopic submucosal dissection (ESD) training, only a flat target lesion can usually be simulated in the normal mucosa. This study aimed to evaluate the feasibility of simulated targets...
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Interobserver Variability and Accuracy of High-Definition Endoscopic Diagnosis for Gastric Intestinal Metaplasia among Experienced and Inexperienced Endoscopists

Hyun YS, Han DS, Bae JH, Park HS, Eun CS

Accurate diagnosis of gastric intestinal metaplasia is important; however, conventional endoscopy is known to be an unreliable modality for diagnosing gastric intestinal metaplasia (IM). The aims of the study were...
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Gastrokine 1 Expression in the Human Gastric Mucosa Is Closely Associated with the Degree of Gastritis and DNA Methylation

Choi WS, Seo HS, Song KY, Yoon JH, Kim O, Nam SW, Lee JY, Park WS

  • KMID: 2372476
  • J Gastric Cancer.
  • 2013 Dec;13(4):232-241.
PURPOSE: Gastrokine 1 plays an important role in gastric mucosal defense. Additionally, the Gastrokine 1-miR-185-DNMT1 axis has been shown to suppress gastric carcinogenesis through regulation of epigenetic alteration. Here, we...
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A Polypoid Mucosa-Associated Lymphoid Tissue Lymphoma of the Stomach Treated with Endoscopic Polypectomy

Min SY, Lee JH, Rhee PL

  • KMID: 2165426
  • Clin Endosc.
  • 2013 Nov;46(6):647-650.
Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is the most common extranodal lymphoma of the gastrointestinal tract. It is usually accompanied by Helicobacter pylori infection, and eradication of H....
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Gastroprotective Potential of Dalbergia sissoo Roxb. Stem Bark against Diclofenac-Induced Gastric Damage in Rats

Khan MI, Khan MR

Objectives Dalbergia sissoo Roxb. stem bark possesses anti-inflammatory, antipyretic, and antioxidant properties. This plant is used traditionally in the Indian system of medicine to treat emesis, ulcers, leucoderma, dysentery, stomach complaints,...
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DNA Double Strand Breaks in Gastric Epithelium with Helicobacter pylori Infection

Chang YJ, Byun SW, Kim HK, Cho YS, Kim SS, Kim JI, Kim JK, Jung ES

BACKGROUND/AIMS: DNA double strand breaks (DSB) is one of the critical types of DNA damage. If unrepaired, DSB is accumulated in the nucleus of cells, the cells become apoptotic or...
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A review on gastric leptin: the exocrine secretion of a gastric hormone

Cammisotto P, Bendayan M

A major advance in the understanding of the regulation of food intake has been the discovery of the adipokine leptin a hormone secreted by the adipose tissue. After crossing the...
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The Relationship between Gastric Juice Nitrate/Nitrite Concentrations and Gastric Mucosal Surface pH

Lee HK, Kim H, Kim HK, Cho YS, Kim BW, Han SW, Maeng LS, Chae HS, Kim HN

PURPOSE: To investigate gastric juice nitrate/nitrite concentration according to mucosal surface pH extent (area) of gastric corpus intimately contacting the gastric juice. MATERIALS AND METHODS: We included ninety-nine patients with dyspepsia....
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Early gastric cancer arising from heterotopic gastric mucosa in the gastric submucosa

Kim DH, Kim KM, Oh SJ, Oh JA, Choi MG, Noh JH, Sohn TS, Bae JM, Kim S

The incidence of heterotopic gastric mucosa located in the submucosa in resected stomach specimens has been reported to be 3.0 to 20.1%. Heterotopic gastric mucosa is thought to be a...
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Gastritis Cystica Polyposa with Gastroduodenal Intussuception: A Case Report

Kwak SH, Bae IH, Park KS, Lee SY, Jeon MH, Cho BS, Kang MH, Ryu DH, Lee HC

Gastritis cystica polyposa is an uncommon benign lesion that normally occurs on the gastric side of a gastroenterostomy site but is rarely found in patients without a prior history of...
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