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Effect of Combination Therapy of Oral Famotidine with Mosapride on Intragastric pH and Gastric Emptying in Rats

Choi HS, Kim EJ, Kim MS, Myung JY, Yu MH, Kim YS, Lee MY

Background/Aims: Studies in healthy humans have reported that the addition of mosapride to acid suppressants resulted in higher intragastric pH than acid suppressant administration alone. We investigated the effect of...
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High-fat Diet Enhances Gastric Contractility, but Abolishes Nesfatin-1-induced Inhibition of Gastric Emptying

Özdemir-Kumral ZN, Koyuncuoğlu T, Arabacı-Tamer S, Çilingir-Kaya , Köroğlu AK, Yüksel M, Yeğen B

  • KMID: 2514685
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):265-278.
  • doi: 10.5056/jnm20206
Background/Aims Gastrointestinal motility changes contribute to development and maintenance of obesity. Nesfatin-1 (NES-1) is involved in central appetite control. The aim is to elucidate effects of NES-1 and high-fat diet (HFD)...
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Delayed Gastric Emptying after Esophagectomy: Management and Prevention

Yang HC, Choi JH, Kim MS, Lee JM

The quality of life associated with eating is becoming an increasingly significant problemfor patients who undergo esophagectomy as a result of the improved survival rate afteresophageal cancer surgery. Delayed gastric...
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A Novel Approach in Spinal Cord Stimulation for Enhancing Gastric Motility: A Preliminary Study on Canines

Tu L, Gharibani , Yang Y, Zhang B, Ji F, Yin J, Chen JDZ

  • KMID: 2500659
  • J Neurogastroenterol Motil.
  • 2020 Jan;26(1):147-159.
  • doi: 10.5056/jnm19101
Background/Aims Gastroparesis is commonly seen in patients with diabetes and functional dyspepsia with no satisfactory therapies. Dysautonomia is one of the main reasons for the imbalanced motility. We hypothesized that...
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Adenocarcinoma of the Proximal Jejunum Misdiagnosed as Gastroparesis

Kim HK, Cho MJ, Ha S, Seo MJ, Moon SG, Oh JH

The prevalence of small bowel cancer is relatively low. The abdominal pain that patients with small bowel cancer present as a symptom is non-specific and often interpreted as a normal...
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Comparing the surgical outcomes of stapled anastomosis versus hand-sewn anastomosis of duodenojejunostomy in pylorus-preserving pancreaticoduodenectomy

Kim DH, Hong SC, Jang JY, Cho JK, Ju YT, Lee YJ, Jung EJ, Jeong SH, Park TJ, Kim JY, Kwag SJ, Park JH, Jeong CY

BACKGROUNDS/AIMS: This study is to evaluate the perioperative outcomes of the circular stapled method versus the hand-sewn method of the duodenojejunostomy (DJ) procedure in pylorus preserving pancreaticoduodenectomy (PPPD). METHODS: In this...
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The Effects of Breast Milk Olfactory Stimulation on Physiological Responses, Oral Feeding Progression and Body Weight in Preterm Infants

Lee EJ

PURPOSE: This study was conducted to evaluate the effect of breast milk olfactory stimulation on physiological responses, oral feeding progression, and body weight in preterm infants. METHODS: A repeated measures design...
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A modified single jejunal loop reconstruction by performing proximal gastrojejunostomy after Whipple's pancreticoduodenectomy in a low-volume hospital

Yücesoy A

BACKGROUNDS/AIMS: It is needed to ensure bowel and biliary tract continuity after pancreaticoduodenectomies. It is possible to find a variety of reconstruction methods in literature. METHODS: We realized a modified reconstruction...
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Association Between Symptoms, Quality of Life, and Gastric Emptying in Dyspeptic Patients

Wuestenberghs F, Juge M, Melchior C, Desprez C, Leroi AM, Gourcerol

  • KMID: 2460483
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):534-543.
  • doi: 10.5056/jnm19060
BACKGROUND/AIMS: Association between symptoms, quality of life and gastric emptying in dyspepsia is inconsistent in the literature. The aim of our study is to investigate if gastric emptying is associated...
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Nutrition Management of Patients with Diabetic Gastroparesis

Lee YK

Gastroparesis is one of complications in diabetic patients which need different management with diabetic patients without complication. Diabetic gastroparesis is a chronic disease and has clinical symptoms such as early...
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Gastric Peroral Endoscopic Myotomy

Chung H, Khashab MA

Gastroparesis (GP) is a syndrome characterized by delayed gastric emptying in the absence of mechanical obstruction of the stomach or proximal small bowel. Currently available dietary and medical therapies are...
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Gastroparesis Updates on Pathogenesis and Management

Liu N, Abell T

Gastroparesis (Gp) is a chronic disease that presents with clinical symptoms of early satiety, bloating, nausea, vomiting, and abdominal pain. Along with these symptoms, an objective finding of delayed gastric...
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Correlation Between Gastric Emptying and Gastric Adaptive Relaxation Influenced by Amino Acids

Uchida M, Kobayashi , Saito C

  • KMID: 2387831
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):400-408.
  • doi: 10.5056/jnm16153
BACKGROUND/AIMS: Amino acids have many physiological activities. We report the correlation between gastric emptying and gastric adaptive relaxation using tryptophan and amino acids with a straight alkyl chain, hydroxylated chain,...
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Should Workers Avoid Consumption of Chilled Fluids in a Hot and Humid Climate?

Brearley M

Despite provision of drinking water as the most common method of occupational heat stress prevention, there remains confusion in hydration messaging to workers. During work site interactions in a hot...
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Severe Delayed Gastric Emptying Induces Non-acid Reflux up to Proximal Esophagus in Neurologically Impaired Patients

Ishii S, Fukahori S, Asagiri K, Tanaka Y, Saikusa N, Hashizume , Yoshida M, Masui D, Komatsuzaki N, Higashidate N, Sakamoto S, Kurahachi , Tsuruhisa , Nakahara H, Yagi M

  • KMID: 2395421
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):533-540.
  • doi: 10.5056/jnm16211
BACKGROUND/AIMS: The aim of this study is to investigate the degree of delayed gastric emptying (DGE) and evaluate how the severity of DGE affects gastroesophageal reflux disease (GERD) in neurologically...
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Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit

Park SY, Burton D, Busciglio , Eckert D, Camilleri

  • KMID: 2367460
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):92-100.
  • doi: 10.5056/jnm16066
BACKGROUND/AIMS: After exclusion of structural diseases, chronic constipation may be associated with normal or slow transit or rectal evacuation disorders. We evaluated: (1) clinical features and anorectal function, (2) difference...
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Benefit of pyloroplasty to prevent gastric stasis in intrahepatic cholangiocarcinoma patients undergoing extensive left-sided lymph node dissection

Cho JW, Lee HW, Hwang S

BACKGROUNDS/AIMS: Intrahepatic cholangiocacinoma (IHCC) can result in spread of tumor cells to the lymph nodes (LNs) around the gastric lesser curvature. Extensive dissection of the gastric lesser curvature can induce...
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The Usefulness of Water-drinking Ultrasonography Combined Test for Evaluating Patients with Functional Dyspepsia

Kugler T

BACKGROUND/AIMS: The major causes of functional dyspepsia (FD) are motility dysfunction and visceral hypersensitivity. Despite the large number of diagnostic tests, there are no convenient methods for evaluation of gastric...
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The Pharmacological Effects of Benachio-F(R) on Rat Gastrointestinal Functions

Poudel BK, Yu JY, Kwon YS, Park HG, Son M, Jun JH, Kim JA, Kim JO

Functional dyspepsia (FD) is a prevalent idiopathic upper gastrointestinal (GI) disorder characterized by diverse symptomatology including epigastric pain or discomfort, postprandial fullness, and early satiety. Although its pathophysiological mechanisms have...
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Leu72Met408 Polymorphism of the Ghrelin Gene Is Associated With Early Phase of Gastric Emptying in the Patients With Functional Dyspepsia in Japan

Yamawaki H, Futagami S, Shimpuku M, Shindo T, Maruki Y, Nagoya H, Kodaka Y, Sato H, Gudis K, Kawagoe T, Sakamoto C

  • KMID: 2381236
  • J Neurogastroenterol Motil.
  • 2015 Jan;21(1):93-102.
  • doi: 10.5056/jnm14086
BACKGROUND/AIMS: There are no available data about the relationship between ghrelin gene genotypes and early phase of gastric emptying in functional dyspepsia (FD) as defined by Rome III classification. METHODS: We...
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