- Dysfunctional Mitochondria Clearance in Situ: Mitophagy in Obesity and Diabetes-Associated Cardiometabolic Diseases
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Tang S, Hao D, Ma W, Liu L, Gao J, Yao P, Yu H, Gan L, Cao Y
- KMID: 2558033
- Diabetes Metab J.
- 2024 Jul;48(4):503-517.
- doi: 10.4093/dmj.2023.0213
Several mitochondrial dysfunctions in obesity and diabetes include impaired mitochondrial membrane potential, excessive mitochondrial reactive oxygen species generation, reduced mitochondrial DNA, increased mitochondrial Ca2+ flux, and mitochondrial dynamics disorders. Mitophagy,... -
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- NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications
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Farrell GC, van Rooyen D, Gan L, Chitturi S
- KMID: 2284261
- Gut Liver.
- 2012 Apr;6(2):149-171.
While non-alcoholic fatty liver disease (NAFLD) is highly prevalent (15% to 45%) in modern societies, only 10% to 25% of cases develop hepatic fibrosis leading to cirrhosis, end-stage liver disease... -
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- Weight Gain during Neoadjuvant Chemotherapy is Associated with Worse Outcome among the Patients with Operable Breast Cancer
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Fang Q, Huang J, Gan L, Shen K, Chen X, Wu B
- KMID: 2458861
- J Breast Cancer.
- 2019 Sep;22(3):399-411.
- doi: 10.4048/jbc.2019.22.e37
PURPOSE: This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients... -
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