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Our understanding and treatment of acute hepatic failure have been limited by the lack of satisfactory animal models. The requirements for a satisfactory animal models are reversibility, reproducibility, death from...
The degree of hepatopathy affecting the synthesis of α2-macroglobulin (α2M) as an acute phase protein in rats was investigated. Hepatopathy was induced in Sprague-Dawley rats by intravenous administration of galactosamine...
BACKGROUND: Though the mivacurium is the short acting nondepolarizing neuromuscular blocking agent, the action duration of it is not prospected in condition of hepatic failure owing to its being metabolized...
BACKGROUND: Duration of action varies in conditions with reduced plasma cholinesterase activity. To evaluate the action duration and recovery of mivacurium under the experimental hepatic failure and cholestasis, the pharmacodynamic...
BACKGROUND/OBJECTIVES: Anti-inflammatory and antioxidative activities of luteolin and luteolin-7-O-glucoside were compared in galactosamine (GalN)/lipopolysaccharide (LPS)-induced hepatitic ICR mice.
MATERIALS/METHODS: Male ICR mice (6 weeks old) were divided into 4 groups: normal...
To determine th effects of experimental extrahepatic cholestasis in the pharmacodynamics of vecumnium, the author administered vecuronium 500 ug/kg intravenously to six normal cats(control group), and into each of six...