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A multicenter, randomized, doubleblind, placebo-controlled trial of amantadine to stimulate awakening in comatose patients resuscitated from cardiac arrest

Coppler PJ, Gagnon DJ, Flickinger KL, Elmer J, Callaway CW, Guyette FX, Doshi A, Steinberg A, Dezfulian C, Moskowitz AL, Donnino M, May TL, Seder DB, Rittenberger JC

Objective We hypothesized that the administration of amantadine would increase awakening of comatose patients resuscitated from cardiac arrest. Methods We performed a prospective, randomized, controlled pilot trial, randomizing subjects to...
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