- A Novel Mutation in the GATA1 Gene Associated with Acute Megakaryoblastic Leukemia in a Korean Down Syndrome Patient
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Kim IS, Park ES, Lim JY, Ki CS, Chi HS
- KMID: 1107540
- J Korean Med Sci.
- 2008 Dec;23(6):1105-1108.
- doi: 10.3346/jkms.2008.23.6.1105
Although acquired mutations in the GATA1 gene have been reported for Down syndrome-related acute megakaryoblastic leukemia (DS-AMKL) in Caucasians, this is the first report of a Korean Down syndrome patient... -
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- CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription
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Uhm TG, Lee SK, Kim BS, Kang JH, Park CS, Rhim TY, Chang HS, Kim DJ, Chung IY
- KMID: 1365904
- Exp Mol Med.
- 2012 Apr;44(4):268-280.
- doi: 10.3858/emm.2012.44.4.022
DNA methylation may regulate gene expression by restricting the access of transcription factors. We have previously demonstrated that GATA-1 regulates the transcription of the CCR3 gene by dynamically interacting with... -
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