- GATA1 Mutation in Transient Myeloproliferative Disorder of Down Syndrome
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Ha JS, Lee WM, Kim JH, Ryoo NH, Jeon DS, Kim JR, Kim HS, Choi BK
- KMID: 1485156
- Korean J Hematol.
- 2008 Mar;43(1):43-47.
- doi: 10.5045/kjh.2008.43.1.43
Children with Down syndrome (DS) have a higher risk of developing leukemia than do healthy children, and they especially have a higher risk for developing transient myeloproliferative disorder (TMD) or... -
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- A Case of Transient Myeloproliferative Disorder Associated with Clonal Trisomy 21 in a Chromosomally Normal Newborn
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Park J, Hong YR, Kong SG
- KMID: 2435414
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):191-196.
- doi: 10.15264/cpho.2018.25.2.191
Transient myeloproliferative disorder (TMD) is similar to congenital leukemia, with leukocytosis, increased peripheral blast cells, and hepatomegaly in the neonatal period. Although TMD occurs only in patients with Down syndrome... -
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- A Novel Mutation in the GATA1 Gene Associated with Acute Megakaryoblastic Leukemia in a Korean Down Syndrome Patient
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Kim IS, Park ES, Lim JY, Ki CS, Chi HS
- KMID: 1107540
- J Korean Med Sci.
- 2008 Dec;23(6):1105-1108.
- doi: 10.3346/jkms.2008.23.6.1105
Although acquired mutations in the GATA1 gene have been reported for Down syndrome-related acute megakaryoblastic leukemia (DS-AMKL) in Caucasians, this is the first report of a Korean Down syndrome patient... -
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- Capsaicin promotes the development of burst-forming nits-erythroid (BFU-E) from mouse bone marrow cells
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Lee SA, Ryu YS, Choi HI, Han IS
- KMID: 1047078
- Exp Mol Med.
- 2007 Jun;39(3):278-283.
Capsaicin, the pungent component of chilli peppers, is known to induce mediators of hematopoiesis. We investigated the effect of capsaicin on hematopoiesis in mouse progenitor cells. Treatment of mouse bone... -
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- CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription
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Uhm TG, Lee SK, Kim BS, Kang JH, Park CS, Rhim TY, Chang HS, Kim DJ, Chung IY
- KMID: 1365904
- Exp Mol Med.
- 2012 Apr;44(4):268-280.
- doi: 10.3858/emm.2012.44.4.022
DNA methylation may regulate gene expression by restricting the access of transcription factors. We have previously demonstrated that GATA-1 regulates the transcription of the CCR3 gene by dynamically interacting with... -
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