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Effect of GABA on the contratility of small intestine isolated from rat

Huh JY, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was designed to investigate the effect of GABA and related substances on the spontaneous contraction of rat small intestine. The rats (Sprague-Dawley), weighing 200-250g, were sacrificed by cervical...
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Effect of diazepam on the oxytocin induced contraction of the isolated rat uterus

Park YK, Lee SH, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was designed to investigate the effect of diazepam on the spontaneous contraction and oxytocin induced contraction of the isolated rat uterus. Female rat (Sprague-Dawley) pretreated with oophorectomy and...
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A Role of Glutamate and GABA Receptors in the Generation of Formalin-induced Impulse Firing of Spinal Dorsal Horn Neurons in the Rat

Bae JY, Jang JH, Jeon YH, Yoon DM, Leem JW, Nam TS, Paik KS

  • KMID: 2199679
  • J Korean Pain Soc.
  • 2003 Dec;16(2):118-132.
BACKGROUND: A peripheral subcutaneous injection of formalin produces biphasic impulse firing of the spinal nociceptive neurons. The roles of excitatory glutamatergic and inhibitory GABAergic receptors were investigated in the formalin-induced...
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Spinal and Peripheral GABA-A and B Receptor Agonists for the Alleviation of Mechanical Hypersensitivity following Compressive Nerve Injury in the Rat

Jeon YH, Yoon DM, Nam TS, Leem JW, Paik GS

BACKGROUND: This study was conducted to investigate the roles of the spinal and peripheral gamma-aminobutyric acid (GABA)-ergic systems for the mechanical hypersensitivity produced by chronic compression of the dorsal root...
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Suppression by Microinjection of Bicuculline into Brain Stem Nuclei of Dorsal Horn Neuron Responsiveness in Neuropathic Rats

Leem JW, Choi Y, Lee JH, Nam TS, Paik KS

  • KMID: 2104785
  • J Korean Pain Soc.
  • 1998 May;11(1):23-29.
BACKGROUND: The present study was conducted to investigate effects of mieroinjection of bicuculline, GABA-A receptor antagonist, into the brain stem nuclei on the dorsal horn neuron responsiveness in rats with an experimental...
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