- Nickel (II)-induced apoptosis and G2/M enrichment
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Lee SH, Kim DK, Seo YR, Woo KM, Kim CS, Cho MH
- KMID: 1109301
- Exp Mol Med.
- 1998 Sep;30(3):171-176.
Treatment with certain DNA-damaging agents induce a complex cellular response comprising pertubation of cell cycle progression and/or apoptosis on proliferating mammalian cells. Our studies were focused on the cellular effects of nickel (II)... -
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- Altered remodeling of nucleolar machineries in cultured hepatocytes treated with thioacetamide
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Jeong JS, Han SY, Kim YH, Choi YC
- KMID: 1066498
- J Korean Med Sci.
- 2001 Feb;16(1):75-82.
- doi: 10.3346/jkms.2001.16.1.75
Thioacetamide (TA) is converted into a hyperacetylating agent which causes hepatic necrosis, regeneration, cirrhosis and cancerous transformation. One of the most characteristic toxicities of TA in rat is observed with... -
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- The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis
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Kim SK, Cho SM, Kim H, Seok H, Kim SO, Kwon TK, Chang JS
- KMID: 2154238
- Exp Mol Med.
- 2013 Apr;45(4):e19.
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report... -
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- Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells
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Hong YB, Kang HJ, Kim HJ, Rosen EM, Dakshanamurthy S, Rondanin R, Baruchello R, Grisolia G, Daniele S, Bae I
- KMID: 1123462
- Exp Mol Med.
- 2009 Mar;41(3):151-160.
- doi: 10.3858/emm.2009.41.3.018
Resveratrol has been reported to possess cancer preventive properties. In this study, we analyzed anti-tumor activity of a newly synthesized resveratrol analog, cis-3,4',5-trimethoxy-3'-hydroxystilbene (hereafter called 11b) towards breast and pancreatic... -
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