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Zebrafish Vascular Development: General and Tissue-Specific Regulation

Nakajima H, Chiba A, Fukumoto M, Morooka N, Mochizuki N

Circulation is required for the delivery of oxygen and nutrition to tissues and organs, as well as waste collection. Therefore, the heart and vessels develop first during embryogenesis. The circulatory system...
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Transplantation of chemically induced liver progenitors as a treatment to ameliorate liver fibrosis

Fukumoto M, Hidaka M, Soyama A, Hara T, Miyamoto D, Matsuguma K, Matsushima H, Imamura H, Adachi T, Eguchi S

Background: Hepatocyte-based regenerative therapy has been reported as an alternative treatment to liver transplantation for end-stage liver disease. We have been investigating the reprogramming of mature hepatocytes to liver progenitors...
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