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Adult-Onset Genetic Leukoencephalopathies With Movement Disorders

Fu MH, Chang YY

Genetic leukoencephalopathies (GLEs) are a group of white matter abnormalities with heterogeneous radiological and phenotypic features. Although these conditions have mostly been described in children, adult-onset cases are increasingly recognized...
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Lipopolysaccharide-induced Autophagy Increases SOX2-positive Astrocytes While Decreasing Neuronal Differentiation in the Adult Hippocampus

Liu WC, Wu CW, Fu MH, Tain YL, Liang CK, Chen IC, Hung CY, Lee YC, Wu KL

  • KMID: 2535062
  • Exp Neurobiol.
  • 2022 Oct;31(5):307-323.
  • doi: 10.5607/en22005
Inflammation alters the neural stem cell (NSC) lineage from neuronal to astrogliogenesis. However, the underlying mechanism is elusive. Autophagy contributes to the decline in adult hippocampal neurogenesis under E. coli...
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