- Primary Carnitine Deficiency and Cardiomyopathy
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Fu L, Huang M, Chen S
- KMID: 2224771
- Korean Circ J.
- 2013 Dec;43(12):785-792.
- doi: 10.4070/kcj.2013.43.12.785
Carnitine is essential for the transfer of long-chain fatty acids from the cytosol into mitochondria for subsequent beta-oxidation. A lack of carnitine results in impaired energy production from long-chain fatty... -
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- Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo
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Yang K, Chen Y, To KK, Wang F, Li D, Chen L, Fu L
- KMID: 2375790
- Exp Mol Med.
- 2017 Mar;49(3):e303.
- doi: 10.1038/emm.2016.168
Alectinib, an inhibitor of anaplastic lymphoma kinase (ALK), was approved by the Food and Drug Administration (FDA) for the treatment of patients with ALK-positive non-small cell lung cancer (NSCLC). Here... -
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- Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells
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He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
- KMID: 1402316
- Exp Mol Med.
- 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.... -
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