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Pharmacokinetic characteristics of fluticasone, salmeterol and tiotropium after concurrent inhalation

Sunwoo J, Rhee SJ, Lee S, Lee SW, Jung J, Son H, Jang IJ

Chronic obstructive pulmonary disease (COPD) is a type of progressive, obstructive lung disease characterized by long-term poor airflow. The symptoms of COPD may be relieved and its progression delayed by...
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Different anti-remodeling effect of nilotinib and fluticasone in a chronic asthma model

Kang HS, Rhee CK, Lee HY, Yoon HK, Kwon SS, Lee SY

BACKGROUND/AIMS: Inhaled corticosteroids are the most effective treatment currently available for asthma, but their beneficial effect against airway remodeling is limited. The tyrosine kinase inhibitor nilotinib has inhibitory activity against...
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Suppressive effects of long-term treatment with inhaled steroids on hypothalamic-pituitary-adrenal axis in asthma

Sim DW, Choi IS, Kim SH

PURPOSE: Long-term treatment with inhaled steroids (ICS), especially fluticasone that developed lately, may suppress the hypothalamic-pituitary-adrenal (HPA) axis. This study investigated the relationship between ICS use and HPA axis suppression...
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An open, Multi center, Randomized, Parallel Group Study to Compare the Effectiveness and Safety of Fluticasone Plus Tulobuterol Versus Twice the Dose of Fluticasone Alone in Asthmatic Children

Jeon YH, Yang HJ, Yoo Y, Kim YH, Jeong JT, Lee HR, Pyun BY

  • KMID: 2314940
  • Pediatr Allergy Respir Dis.
  • 2009 Jun;19(2):125-136.
PURPOSE: We aim to compare the effectiveness and safety of fluticasone propionate (Flt) plus tulobuterol (Hk) versus high-dose Flt alone in controlling asthma in children. METHODS: Fifty three children aged 4...
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Effect of Roxithromycin and Intranasal Fluticasone Spray in Reducing Symptoms of Chronic Sinusitis, Polyp Size and IL-4 in Allergic Patients

Kim BG, Lee DM, Jo JH, Jung DG, Kang JM, Kim SW

  • KMID: 2223307
  • J Rhinol.
  • 2003 Nov;10(1, 2):37-41.
Nasal polyp is an intractable condition usually associated with chronic hyperplastic sinusitis with allergic rhinitis. IL-4 is known to contribute to the inflammatory reaction by enhancing binding of inflammatory cells...
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Effect of Inhaled Fluticasone Propionate on Hypothalamic-Pituitary-Adrenal Axis in Bronchial Asthma Patient

Hwang JK, Lee HM, No YW, Park GY, Park CW, Park JK, Jeong SH, Nam GH, Kim HK, Park HY, Kang MH

BACKGROUND: Inhaled glucocorticoids are the medical treatment of choice in asthma patients. Fluticasone propionate is one of the most effective inhaled corticosteroids and has been reported to have minimal effect...
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Fluticasone Propionate and Beclomethasone Dipropionate in Asthmatic Patients

Yang DK, Kim YS, Ahn CM, Ko WK, Chang J, Kim SK, Lee WY

  • KMID: 2318245
  • Tuberc Respir Dis.
  • 1999 Nov;47(5):629-641.
BACKGROUND: Corticosteroid is most potent and effective anti-inflammatory medication currently available and inhaled form has been used in the long-term control of asthma. Fluticasone propionate(Flixotide/Flovent : FP) is highly potent...
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Effect of Short Term Treatment with Different Dosage of Inhaled Flucatisone Propionate on Basal Cortisol Concentration

Kim HJ, Kim HS, Lee H, Lim ST, Moon SG, Park JH, Lee HB, Lee YC, Rhee YK

  • KMID: 2318086
  • Tuberc Respir Dis.
  • 1997 Oct;44(5):1063-1071.
BACKGROUND: The efficacy of oral corticosteroids in the treatment of chronic asthma is undisputed, but their long-term use is associated with adverse side-effects, including supression of the hypothalamic-pituitary adrenal axis...
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