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Modified Release Tacrolimus

First MR, Fitzsimmons WE

Modified Release (MR) tacrolimus is an extended release formulation of tacrolimus (Prograf (R) ) administered once daily in the morning. In healthy volunteers, the MR tacrolimus formulation given qd AM...
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FK778, A Synthetic Malononitrilamide

Fitzsimmons WE, First MR

FK778 is a synthetic malononitrilamide (MNA) that has been demonstrated to have both both immunosuppressive and anti-proliferative activities. The MNAs inhibit both T-cell and B-cell function by blocking de novo...
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